- Hemagglutinin Receptor Binding Avidity Drives Influenza A Virus Antigenic Drift
[作者：Hensley, SE; Das, SR; Bailey, AL; Schmidt, LM; Hickman, HD; Jayaraman, A; Viswanathan, K; Raman, R; Sasisekharan, R; Bennink, JR; Yewdell, JW,期刊：Science, 页码：734-736 , 文章类型： Article，,卷期：2009年326-5953]
- Rapid antigenic evolution in the influenza A virus hemagglutinin precludes effective vaccination with existing vaccines. To understand this phenomenon, we passaged virus in mice immunized with influenza vaccine. Neutrali...
- The Transmissibility and Control of Pandemic Influenza A (H1N1) Virus
[作者：Yang, Y; Sugimoto, JD; Halloran, ME; Basta, NE; Chao, DL; Matrajt, L; Potter, G; Kenah, E; Longini, IM,期刊：Science, 页码：729-733 , 文章类型： Article，,卷期：2009年326-5953]
- Pandemic influenza A (H1N1) 2009 (pandemic H1N1) is spreading throughout the planet. It has become the dominant strain in the Southern Hemisphere, where the influenza season has now ended. Here, on the basis of reported ...
- Quantifying the Impact of Immune Escape on Transmission Dynamics of Influenza
[作者：Park, AW; Daly, JM; Lewis, NS; Smith, DJ; Wood, JLN; Grenfell, BT,期刊：Science, 页码：726-728 , 文章类型： Article，,卷期：2009年326-5953]
- Influenza virus evades prevailing natural and vaccine-induced immunity by accumulating antigenic change in the haemagglutinin surface protein. Linking amino acid substitutions in haemagglutinin epitopes to epidemiology h...
- An E3 Ligase Possessing an Iron-Responsive Hemerythrin Domain Is a Regulator of Iron Homeostasis
[作者：Salahudeen, AA; Thompson, JW; Ruiz, JC; Ma, HW; Kinch, LN; Li, QM; Grishin, NV; Bruick, RK,期刊：Science, 页码：722-726 , 文章类型： Article，,卷期：2009年326-5953]
- Cellular iron homeostasis is maintained by the coordinate posttranscriptional regulation of genes responsible for iron uptake, release, use, and storage through the actions of the iron regulatory proteins IRP1 and IRP2. ...
- Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
[作者：Vashisht, AA; Zumbrennen, KB; Huang, XH; Powers, DN; Durazo, A; Sun, DH; Bhaskaran, N; Persson, A; Uhlen, M; Sangfelt, O; Spruck, C; Leibold, EA; Wohlschlegel, JA,期刊：Science, 页码：718-721 , 文章类型： Article，,卷期：2009年326-5953]
- Eukaryotic cells require iron for survival and have developed regulatory mechanisms for maintaining appropriate intracellular iron concentrations. The degradation of iron regulatory protein 2 (IRP2) in iron-replete cells...
- Improved Attribution of Climate Forcing to Emissions
[作者：Shindell, DT; Faluvegi, G; Koch, DM; Schmidt, GA; Unger, N; Bauer, SE,期刊：Science, 页码：716-718 , 文章类型： Article，,卷期：2009年326-5953]
- Evaluating multicomponent climate change mitigation strategies requires knowledge of the diverse direct and indirect effects of emissions. Methane, ozone, and aerosols are linked through atmospheric chemistry so that emi...
|