- Conversion of Sox17 into a Pluripotency Reprogramming Factor by Reengineering Its Association with Oct4 on DNA
[作者:Jauch, R; Aksoy, I; Hutchins, AP; Ng, CKL; Tian, XF; Chen, JX; Palasingam, P; Robson, P; Stanton, LW; Kolatkar, PR,期刊:Stem Cells, 页码:940-951 , 文章类型: Article,,卷期:2011年29-6]
- Very few proteins are capable to induce pluripotent stem (iPS) cells and their biochemical uniqueness remains unexplained. For example, Sox2 cooperates with other transcription factors to generate iPS cells, but Sox17, d...
- Dissection of the Biphasic Nature of Hypoxia-Induced Motogenic Action in Bone Marrow-Derived Human Mesenchymal Stem Cells
[作者:Busletta, C; Novo, E; Di Bonzo, LV; Povero, D; Paternostro, C; Ievolella, M; Mareschi, K; Ferrero, I; Cannito, S; Compagnone, A; Bandino, A; Colombatto, S; Fagioli, F; Parola, M,期刊:Stem Cells, 页码:952-963 , 文章类型: Article,,卷期:2011年29-6]
- Hypoxic conditions have been reported to facilitate preservation of undifferentiated mesenchymal stem cell (MSC) phenotype and positively affect their colony-forming potential, proliferation, and migration/mobilization. ...
- Single Transcription Factor Reprogramming of Hair Follicle Dermal Papilla Cells to Induced Pluripotent Stem Cells
[作者:Tsai, SY; Bouwman, BA; Ang, YS; Kim, SJ; Lee, DF; Lemischka, IR; Rendl, M,期刊:Stem Cells, 页码:964-971 , 文章类型: Article,,卷期:2011年29-6]
- Reprogramming patient-specific somatic cells into induced pluripotent stem (iPS) cells has great potential to develop feasible regenerative therapies. However, several issues need to be resolved such as ease, efficiency,...
- Differentiation of Induced Pluripotent Stem Cells of Swine into Rod Photoreceptors and Their Integration Into the Retina
[作者:Zhou, L; Wang, W; Liu, YQ; de Castro, JF; Ezashi, T; Telugu, BPVL; Roberts, RM; Kaplan, HJ; Dean, DC,期刊:Stem Cells, 页码:972-980 , 文章类型: Article,,卷期:2011年29-6]
- Absence of a regenerative pathway for damaged retina following injury or disease has led to experiments using stem cell transplantation for retinal repair, and encouraging results have been obtained in rodents. The swine...
- Strontium Enhances Osteogenic Differentiation of Mesenchymal Stem Cells and In Vivo Bone Formation by Activating Wnt/Catenin Signaling
[作者:Yang, F; Yang, DZ; Tu, J; Zheng, QX; Cai, LT; Wang, LP,期刊:Stem Cells, 页码:981-991 , 文章类型: Article,,卷期:2011年29-6]
- Strontium ranelate is a newly approved drug that can reduce the risk of vertebral fracture, which is attributed to its dual function in increasing the bone formation and decreasing the bone resorption. Strontium-containi...
- Reprogramming of Postnatal Neurons into Induced Pluripotent Stem Cells by Defined Factors
[作者:Kim, J; Lengner, CJ; Kirak, O; Hanna, J; Cassady, JP; Lodato, MA; Wu, S; Faddah, DA; Steine, EJ; Gao, Q; Fu, DD; Dawlaty, M; Jaenisch, R,期刊:Stem Cells, 页码:992-1000 , 文章类型: Article,,卷期:2011年29-6]
- Pluripotent cells can be derived from different types of somatic cells by nuclear reprogramming through the ectopic expression of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc. However, it is unclear whether ...
- Toll-Like Receptor-3-Activated Human Mesenchymal Stromal Cells Significantly Prolong the Survival and Function of Neutrophils
[作者:Cassatella, MA; Mosna, F; Micheletti, A; Lisi, V; Tamassia, N; Cont, C; Calzetti, F; Pelletier, M; Pizzolo, G; Krampera, M,期刊:Stem Cells, 页码:1001-1011 , 文章类型: Article,,卷期:2011年29-6]
- Bone marrow-derived mesenchymal stromal cells (BM-MSCs) are stromal precursors endowed with extensive immunomodulative properties. In this study, we aimed to assess whether Toll-like receptor-3 (TLR3)- and TLR4-activated...
- Concise Review: Quiescent and Active States of Endogenous Adult Neural Stem Cells: Identification and Characterization
[作者:Wang, YZ; Plane, JM; Jiang, P; Zhou, CJJ; Deng, WB,期刊:Stem Cells, 页码:907-912 , 文章类型: Review,,卷期:2011年29-6]
- The adult mammalian central nervous system (CNS) lacks the capacity for regeneration, making it a highly sought-after topic for researchers. The identification of neural stem cells (NSCs) in the adult CNS wiped out a lon...
- Concise Review: Mesenchymal Stem Cells for Acute Lung Injury: Role of Paracrine Soluble Factors
[作者:Lee, JW; Fang, XH; Krasnodembskaya, A; Howard, JP; Matthay, MA,期刊:Stem Cells, 页码:913-919 , 文章类型: Review,,卷期:2011年29-6]
- Morbidity and mortality have declined only modestly in patients with clinical acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), despite extensive research into the pathophysiology. Current treatment...
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