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Conversion of Sox17 into a Pluripotency Reprogramming Factor by Reengineering Its Association with Oct4 on DNA

  作者 Jauch, R; Aksoy, I; Hutchins, AP; Ng, CKL; Tian, XF; Chen, JX; Palasingam, P; Robson, P; Stanton, LW; Kolatkar, PR  
  选自 期刊  Stem Cells;  卷期  2011年29-6;  页码  940-951  
  关联知识点  
 

[摘要]Very few proteins are capable to induce pluripotent stem (iPS) cells and their biochemical uniqueness remains unexplained. For example, Sox2 cooperates with other transcription factors to generate iPS cells, but Sox17, despite binding to similar DNA seque

 
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