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Reprogramming of Postnatal Neurons into Induced Pluripotent Stem Cells by Defined Factors

  作者 Kim, J; Lengner, CJ; Kirak, O; Hanna, J; Cassady, JP; Lodato, MA; Wu, S; Faddah, DA; Steine, EJ; Gao, Q; Fu, DD; Dawlaty, M; Jaenisch, R  
  选自 期刊  Stem Cells;  卷期  2011年29-6;  页码  992-1000  
  关联知识点  
 

[摘要]Pluripotent cells can be derived from different types of somatic cells by nuclear reprogramming through the ectopic expression of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc. However, it is unclear whether postmitotic neurons are susceptible

 
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