【文章名】Directed Expression of Gata2, Mash1, and Foxa2 Synergize to Induce the Serotonergic Neuron Phenotype During In Vitro Differentiation of Embryonic Stem Cells
Directed Expression of Gata2, Mash1, and Foxa2 Synergize to Induce the Serotonergic Neuron Phenotype During In Vitro Differentiation of Embryonic Stem Cells
[摘要]:Investigation of serotonergic neuronal activity and its relationship to disease has been limited by a lack of physiologically relevant in vitro cell models. Serotonergic neurons derived from embryonic stem cells (ESCs) could provide a platform for such st