- Analogues of (3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and in Vitro and in Vivo Opioid Receptor Antagonist Activity
[作者：RUNYON SCOTT P; BRIEADDY LAWRENCE E; MASCARELLA S WAYNE; THOMAS JAMES B; NAVARRO HERNAN A; HOWARD JAMES L; POLLARD GERALD T; CARROLL F IVY,期刊：Journal of Medicinal Chemistry, 页码：5290-5301 , 文章类型： Article，,卷期：2010年53-14]
- The synthesis of compounds 6, 7a,b, 8a,b, 9a,b, and 10a,b where the amino -NH- group of JDTic (3) was replaced with an aromatic =CH-, CH2, O, S, or SO group was accomplished and used to further characterize the SAR of th...
- Peptide HIV-1 Integrase Inhibitors from HIV-1 Gene Products
[作者：SUZUKI SHINTARO; URANO EMIKO; HASHIMOTO CHIC; TSUTSUMI HIROSHI; NAKAHARA TORU; TANAKA TOMOHIRO; NAKANISHI YUTA; MADDALI KASTHURAIAH; HAN YAN; HAMATAKE MAKIKO; MIYAUCHI KOSUKE; POMMIE YVES; BEUTLER JOHN A; SUGIURA WATARU; FUJI HIDEYOSHI; HOSHINO TYUJI; ITOTANI KYOKO; NOMURA WATARU; NARUMI TETSUO; YAMAMOTO NAOKI; KOMANO JUN A; TAMAMURA HIROKAZU,期刊：Journal of Medicinal Chemistry, 页码：5356-5360 , 文章类型： Article，,卷期：2010年53-14]
- Anti-HIV peptides with inhibitory activity against HIV-1 integrase (IN) have been found in overlapping peptide libraries derived from HIV-1 gene products. In a strand transfer assay using IN, inhibitory active peptides w...
|