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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共17条记录   Reactivity of Oxazol-5-(4H)-ones and Their Application toward Natural Product Synthesis [作者：HEWLETT N M; HUPP C D; TEPE J J,期刊：Synthesis, 页码：2825-2839 , 文章类型： Article，,卷期：2009年-17] This work reviews the reactivity of oxazolones and their application in the synthesis of natural products. In particular, the focus is on the development and scope of oxazolone-mediated ene-type reactions, 1,3-dipolar cy... Towards the Total Synthesis of 3-Hydroxyvibsanin E [作者：SCHWARTZ BRETT D; DENTON JUSTIN R; BERNHARDT PAUL V; DAVIES HUW M L; WILLIAMS CRAIG M,期刊：Synthesis, 页码：2840-2846 , 文章类型： Article，,卷期：2009年-17] The synthesis of a silyl-protected derivative of 3-hydroxyvibsanin E has been achieved. The key step is a regio- and stereoselective C-H hydroxylation of an advanced tricyclic intermediate by means of a Rubottom oxidatio... Structure Investigations of (ent)-Cladospolide D by De Novo Synthesis and Kinetic and Thermodynamic Isomerization [作者：XING YALAN; PENN JOHN H; ODOHERTY GEORGE A,期刊：Synthesis, 页码：2847-2854 , 文章类型： Article，,卷期：2009年-17] The de novo asymmetric synthesis of cladospolides B and C and (ent)-cladospolide D has been achieved from achiral non-l-yne. The 11-13-step route relies upon a Noyori reduction and a KAPA promoted alkyne zipper reaction ... Stereodivergent Approach to Both C2,8a-syn and C2,8a-anti Relative Stereochemical Manifolds in the Lepadin Family via a TiCl4-Promoted Aza-[3+3] Annulation [作者：LI GANG; CARLSON LAUREN J; SAGAMANOVA IRINA K; SLAFER BRIAN W; HSUNG RICHARD P; GILARDI CLAUDIO; SKLENICKA HEATHER M; SYDORENKO NADIYA,期刊：Synthesis, 页码：2905-2914 , 文章类型： Article，,卷期：2009年-17] Details in developing a stereodivergent approach to the lepadin family and establishing an entry to both C2,8a-syn and C2,8a-anti relative stereochemical manifolds through a common intermediate are described here. This w... New Applications of PhI(OAc)(2) in Synthesis: Total Synthesis and SAR Development of Potent Antitumor Natural Product Psymberin/Irciniastatin A [作者：SHAO NING; HUANG XIANHAI; PALANI ANANDAN; ASLANIAN ROBERT; BUEVICH ALEXEI; PIWINSKI JOHN; HURYK ROBERT; SEIDELDUGAN CYNTHIA,期刊：Synthesis, 页码：2855-2872 , 文章类型： Article，,卷期：2009年-17] A novel PhI(OAc)(2)-mediated oxidative cyclization reaction is discovered for the synthesis of alpha-oxy N-acyl aminals and hemiaminals in good yields from readily synthesized N-acyl enamines. This methodology represents... Total Synthesis of Largazole - Devolution of a Novel Synthetic Strategy [作者：WANG BO; FORSYTH CRAIG J,期刊：Synthesis, 页码：2873-2880 , 文章类型： Article，,卷期：2009年-17] The cyanobacterial isolate largazole embodies a compelling combination of a relatively simple, yet unique cyclic depsipeptide structure with remarkable levels of selective cytotoxicity against cancer cell lines versus no... Formal Total Synthesis of Palmerolide A [作者：JAEGEL JULIA; MAIER MARTIN E,期刊：Synthesis, 页码：2881-2892 , 文章类型： Article，,卷期：2009年-17] A concise route to macrolactone 38, an advanced intermediate of the Nicolaou/Chen synthesis of palmerolide A, is described. Key steps in our synthesis include a Noyori transfer hydrogenation of all alkynone, chain extens... Total Synthesis of Bongkrekic Acid via Sequential Suzuki-Miyaura Coupling Reactions [作者：KANEMATSU MAKOTO; SHINDO MITSURU; YOSHIDA MASAHIRO; SHISHIDO KOZO,期刊：Synthesis, 页码：2893-2904 , 文章类型： Article，,卷期：2009年-17] An efficient total synthesis of (+)-bongkrekic acid, a potent apoptosis inhibitor, has been accomplished by employing a convergent strategy based on the Suzuki-Miyaura coupling of three fully functionalized segments. Stereochemical Assignments of the Chlorinated Residues in Victorin C [作者：DUROW AMANDA C; BUTTS CRAIG; WILLIS CHRISTINE L,期刊：Synthesis, 页码：2954-2962 , 文章类型： Article，,卷期：2009年-17] Victorins are cyclic pentapeptide natural products isolated from the fungus Cochliobus victoriae. Using a combination of synthesis and spectroscopic methods we have assigned the geometry of the vinyl chloride residue and... Enantioselective Aldol Reaction of Tetrasubstituted Ketene Silyl Acetals with Achiral Aldehydes for the Construction of Asymmetric Tertiary Alcohols: An Application for the Divergent Total Syntheses of Buergerinins F and G [作者：SHIINA ISAMU; IIZUMI TAKASHI; YAMAI YUSUKE; KAWAKITA YOICHI; YOKOYAMA KAZUTOSHI; YAMADA YOKO,期刊：Synthesis, 页码：2915-2926 , 文章类型： Article，,卷期：2009年-17] The asymmetric aldol reaction of heteroatom-substituted ketene silyl acetals with achiral aldehydes has been developed by the promotion of tin(II) triflate coordinated with a chiral diamine to afford the corresponding al... Second-Generation, Biomimetic Total Synthesis of Chaetominine [作者：COSTE ALEXIS; KARTHIKEYAN GANESAN; COUTY FRANCOIS; EVANO GWILHERM,期刊：Synthesis, 页码：2927-2934 , 文章类型： Article，,卷期：2009年-17] A straightforward total synthesis of the potent anticancer agent (-)-chaetominine is reported. Central to this synthesis was a biomimetic oxidative cyclization of a tryptophanyl-alanine dipeptide, which provided a fully ... Total Synthesis of (+)-Fostriecin and (+)-Phoslactomycin B [作者：SHIBAHARA SETSUYA; FUJINO MASATAKA; TASHIRO YASUMASA; OKAMOTO NANAKO; ESUMI TOMOYUKI; TAKAHASHI KEISUSKE; ISHIHARA JUN; HATAKEYAMA SUSUMI,期刊：Synthesis, 页码：2935-2953 , 文章类型： Article，,卷期：2009年-17] (+)-Fostriecin and (+)-phoslactornycin B, which are potent and selective inhibitors of protein phosphatase, were synthesized by a highly enantio- and stereoselective approach that enabled us to prepare all possible isome... Studies of the Asymmetric Total Synthesis of Clavilactone D by the 'Lariat' Cyclization Strategy [作者：YOSHIMITSU TAKEHIKO; NOJIMA SHOJI; HASHIMOTO MASASHI; TSUKAMOTO KOJI; TANAKA TETSUAKI,期刊：Synthesis, 页码：2963-2969 , 文章类型： Article，,卷期：2009年-17] A route to the core structure of clavilactone D, a new member of the tyrosine kinase inhibitors, is reported. The route employs sequential cyclization initiated by iodo etherification followed by Friedel-Crafts cyclizati... Formal Synthesis of Salinosporamide A Starting from D-Glucose [作者：MOMOSE TAKAYUKI; KAIYA YUJI; HASEGAWA JUNICHI; SATO TAKAAKI; CHIDA NORITAKA,期刊：Synthesis, 页码：2983-2991 , 文章类型： Article，,卷期：2009年-17] A formal synthesis of salinosporarmde A is described. The tertiary alcohol function in salinosporarmde A was stereoselectively generated via the substrate control by the reaction of a cyclic ketone derived from D-glucose... Synthesis of Bioactive Natural Products by Asymmetric syn- and anti-Aldol Reactions [作者：GHOSH ARUN K; DAWSON ZACHARY L,期刊：Synthesis, 页码：2992-3002 , 文章类型： Article，,卷期：2009年-17] The use of several variants of the asymmetric aldol reaction as key steps in the syntheses of bioactive target molecules is described. Total Synthesis of the Leucetta-Derived Alkaloid Calcaridine A [作者：KOSWATTA PANDUKA B; SIVAPPA RASAPALLI; DIAS H V RASIKA; LOVELY CARL J,期刊：Synthesis, 页码：2970-2982 , 文章类型： Article，,卷期：2009年-17] A biomimetically guided total synthesis of the Leucetta-derived aminoimidazole alkaloid, calcaridine A, is described. The synthesis relies on position selective metalations of a 4,5-diiodoimidazole derivative to provide ...