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Total Synthesis of (+)-Fostriecin and (+)-Phoslactomycin B

  作者 SHIBAHARA SETSUYA; FUJINO MASATAKA; TASHIRO YASUMASA; OKAMOTO NANAKO; ESUMI TOMOYUKI; TAKAHASHI KEISUSKE; ISHIHARA JUN; HATAKEYAMA SUSUMI  
  选自 期刊  Synthesis;  卷期  2009年-17;  页码  2935-2953  
  关联知识点  
 

[摘要](+)-Fostriecin and (+)-phoslactornycin B, which are potent and selective inhibitors of protein phosphatase, were synthesized by a highly enantio- and stereoselective approach that enabled us to prepare all possible isomers at both the C11 secondary alcohol position and the Delta(12)-double bond.

 
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