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  • SYNYHESIS AND ANTI-HEPATITIS C VIRUS ACTIVITY OF MORPHOLINO TRIAZINE DERIVATIVES
    [作者:MISAWA TAKASHI; SALIM MOHAMMED T A; OKAMOTO MIKA; BABA MASANORI; AOYAMA HIROSHI; HASHIMOTO YUICHI; SUGITA KAZUYUKI,期刊:Heterocycles, 页码:1419-1426 , 文章类型: Article,,卷期:2010年81-6]
  • A series of morpholino triazines was synthesized and evaluated for anti-hepatitis C virus (HCV) activity. Incorporation of OMe, CN and F into the phenyl moiety afforded analogues with moderate potency and good selectivit...
  • PYRROLIZIDINE ALKALOIDS FROM THE ROOTS OF PARIS VERTICILLATA
    [作者:KIM KI HYUN; LEE KYU HA; CHOI SANG UN; KIM KYUNG RAN; LEE KANG RO,期刊:Heterocycles, 页码:1493-1502 , 文章类型: Article,,卷期:2010年81-6]
  • Three new pyrrolizidine alkaloids, verticillatins A (1), B (2), and C (3), together with seven known pyrrolizidine alkaloids (4-10), were isolated from the roots of Paris verticillata (Liliaceae). Their structures were d...
  • NOVEL AND PRACTICAL SYNTHESIS OF CANDESARTAN CILEXETIL
    [作者:MAO YONGJUN; XIONG RUISHENG; LIU ZHENG; LI HAIHONG; SHEN JINGKANG; SHEN JINGSHAN,期刊:Heterocycles, 页码:1503-1508 , 文章类型: Article,,卷期:2010年81-6]
  • A novel and convergent synthetic route of candesartan cilexetil (API of Atacand), an effective angiotensin II receptor blocker, is described. Cleavage of the N-Boc and N-trityl protective group are implemented simultaneo...
  • BRIDGED NUCLEIC ACIDS: DEVELOPMENT, SYNTHESIS AND PROPERTIES
    [作者:OBIKA SATOSHI; RAHMAN S M ABDUR; FUJISAKA AKI; KAWADA YUJI; BABA TAKESHI; IMANISHI TAKESHI,期刊:Heterocycles, 页码:1347-1392 , 文章类型: Review,,卷期:2010年81-6]
  • Restricting the sugar moiety of a nucleic acid to a single conformation can be accomplished by forming a bridge in the sugar. A large number of bridged nucleic acids with variable bridged structures and conformations hav...