- Structure of WDR5 Bound to Mixed Lineage Leukemia Protein-1 Peptide
[作者:Patel, A; Dharmarajan, V; Cosgrove, MS,期刊:Journal of Biological Chemistry, 页码:32158-32161 , 文章类型: Article,,卷期:2008年283-47]
- The mixed lineage leukemia protein-1 (MLL1) catalyzes histone H3 lysine 4 methylation and is regulated by interaction with WDR5 (WD-repeat protein-5), RbBP5 (retinoblastoma-binding protein-5), and the Ash2L (absent, smal...
- Effects of Grape Seed-derived Polyphenols on Amyloid beta-Protein Self-assembly and Cytotoxicity
[作者:Ono, K; Condron, MM; Ho, L; Wang, J; Zhao, W; Pasinetti, GM; Teplow, DB,期刊:Journal of Biological Chemistry, 页码:32176-32187 , 文章类型: Article,,卷期:2008年283-47]
- Epidemiological evidence suggests that moderate consumption of red wine reduces the incidence of Alzheimer disease (AD). To study the protective effects of red wine, experiments recently were executed in the Tg2576 mouse...
- Abscisic Acid Is an Endogenous Stimulator of Insulin Release from Human Pancreatic Islets with Cyclic ADP Ribose as Second Messenger
[作者:Bruzzone, S; Bodrato, N; Usai, C; Guida, L; Moreschi, I; Nano, R; Antonioli, B; Fruscione, F; Magnone, M; Scarfi, S; De Flora, A; Zocchi, E,期刊:Journal of Biological Chemistry, 页码:32188-32197 , 文章类型: Article,,卷期:2008年283-47]
- Abscisic acid (ABA) is a plant stress hormone recently identified as an endogenous pro-inflammatory cytokine in human granulocytes. Because paracrine signaling between pancreatic beta cells and inflammatory cells is incr...
- G9a and HP1 Couple Histone and DNA Methylation to TNF alpha Transcription Silencing during Endotoxin Tolerance
[作者:El Gazzar, M; Yoza, BK; Chen, X; Hu, J; Hawkins, GA; Mccall, CE,期刊:Journal of Biological Chemistry, 页码:32198-32208 , 文章类型: Article,,卷期:2008年283-47]
- TNF alpha gene expression is silenced in the endotoxin tolerant phenotype that develops in blood leukocytes after the initial activation phase of severe systemic inflammation or sepsis. The silencing phase can be mimicke...
- Two Active Forms of Zymomonas mobilis Levansucrase AN ORDERED MICROFIBRIL STRUCTURE OF THE ENZYME PROMOTES LEVAN POLYMERIZATION
[作者:Goldman, D; Lavid, N; Schwartz, A; Shoham, G; Danino, D; Shoham, Y,期刊:Journal of Biological Chemistry, 页码:32209-32217 , 文章类型: Article,,卷期:2008年283-47]
- Fructansucrases, members of glycoside hydrolase family 68, catalyze both sucrose hydrolysis and the polymerization of fructose to beta-D-fructofuranose polymers. The resulting fructan polymers are distinguished by the na...
- Histone N-terminal Tails Interfere with Nucleosome Traversal by RNA Polymerase II
[作者:Ujvari, A; Hsieh, FK; Luse, SW; Studitsky, VM; Luse, DS,期刊:Journal of Biological Chemistry, 页码:32236-32243 , 文章类型: Article,,卷期:2008年283-47]
- We determined the effect of the N-terminal histone tails on nucleosome traversal by yeast and human RNA polymerase II (pol II). Removal of H2A/H2B tails, H3/H4 tails, or all tails increased complete traversal of the nucl...
- Hepatocyte Growth Factor/c-MET Axis-mediated Tropism of Cord Blood-derived Unrestricted Somatic Stem Cells for Neuronal Injury
[作者:Trapp, T; Kogler, G; El-Khattouti, A; Sorg, RV; Besselmann, M; Focking, M; Buhrle, CP; Trompeter, I; Fischer, JC; Wernet, P,期刊:Journal of Biological Chemistry, 页码:32244-32253 , 文章类型: Article,,卷期:2008年283-47]
- An under-agarose chemotaxis assay was used to investigate whether unrestricted somatic stem cells (USSC) that were recently characterized in human cord blood are attracted by neuronal injury in vitro. USSC migrated towar...
- BRD7, a Novel PBAF-specific SWI/SNF Subunit, Is Required for Target Gene Activation and Repression in Embryonic Stem Cells
[作者:Kaeser, MD; Aslanian, A; Dong, MQ; Yates, JR; Emerson, BM,期刊:Journal of Biological Chemistry, 页码:32254-32263 , 文章类型: Article,,卷期:2008年283-47]
- The composition of chromatin-remodeling complexes dictates how these enzymes control transcriptional programs and cellular identity. In the present study we investigated the composition of SWI/SNF complexes in embryonic ...
- Asymmetry in the Lipid Affinity of Bihelical Amphipathic Peptides A STRUCTURAL DETERMINANT FOR THE SPECIFICITY OF ABCA1-DEPENDENT CHOLESTEROL EFFLUX BY PEPTIDES
[作者:Sethi, AA; Stonik, JA; Thomas, F; Demosky, SJ; Amar, M; Neufeld, E; Brewer, HB; Davidson, WS; D'Souza, W; Sviridov, D; Remaley, AT,期刊:Journal of Biological Chemistry, 页码:32273-32282 , 文章类型: Article,,卷期:2008年283-47]
- ApoA-I contains a tandem array of amphipathic helices with varying lipid affinity, which are critical in its ability to bind and remove lipids from cells by the ABCA1 transporter. In this study, the effect of asymmetry i...
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