- Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales
[作者:Paytubi, S; McMahon, SA; Graham, S; Liu, HT; Botting, CH; Makarova, KS; Koonin, EV; Naismith, JH; White, MF,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:E398-E405 , 文章类型: Article,,卷期:2012年109-7]
- ssDNA-binding proteins (SSBs) based on the oligonucleotide-binding fold are considered ubiquitous in nature and play a central role in many DNA transactions including replication, recombination, and repair. We demonstrat...
- Cofilin under control of beta-arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learning
[作者:Pontrello, CG; Sun, MY; Lin, A; Fiacco, TA; Defea, KA; Ethell, IM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:E442-E451 , 文章类型: Article,,卷期:2012年109-7]
- Dendritic spines are dynamic, actin-rich structures that form the postsynaptic sites of most excitatory synapses in the brain. The F-actin severing protein cofilin has been implicated in the remodeling of dendritic spine...
- Tight coevolution of proliferating cell nuclear antigen (PCNA)-partner interaction networks in fungi leads to interspecies network incompatibility
[作者:Zamir, L; Zaretsky, M; Fridman, Y; Ner-Gaon, H; Rubin, E; Aharoni, A,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:E406-E414 , 文章类型: Article,,卷期:2012年109-7]
- The structure and connectivity of protein-protein interaction (PPI) networks are maintained throughout evolution by coordinated changes (coevolution) of network proteins. Despite extensive research, relatively little is ...
- Daily bursts of biogenic cyanogen bromide (BrCN) control biofilm formation around a marine benthic diatom
[作者:Vanelslander, B; Paul, C; Grueneberg, J; Prince, EK; Gillard, J; Sabbe, K; Pohnert, G; Vyverman, W,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2412-2417 , 文章类型: Article,,卷期:2012年109-7]
- The spatial organization of biofilms is strongly regulated by chemical cues released by settling organisms. However, the exact nature of these interactions and the repertoire of chemical cues and signals that micro-organ...
- Severe mammal declines coincide with proliferation of invasive Burmese pythons in Everglades National Park
[作者:Dorcas, ME; Willson, JD; Reed, RN; Snow, RW; Rochford, MR; Miller, MA; Meshaka, WE; Andreadis, PT; Mazzotti, FJ; Romagosa, CM; Hart, KM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2418-2422 , 文章类型: Article,,卷期:2012年109-7]
- Invasive species represent a significant threat to global biodiversity and a substantial economic burden. Burmese pythons, giant constricting snakes native to Asia, now are found throughout much of southern Florida, incl...
- Regional drought-induced reduction in the biomass carbon sink of Canada's boreal forests
[作者:Ma, ZH; Peng, CH; Zhu, QA; Chen, H; Yu, GR; Li, WZ; Zhou, XL; Wang, WF; Zhang, WH,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2423-2427 , 文章类型: Article,,卷期:2012年109-7]
- The boreal forests, identified as a critical "tipping element" of the Earth's climate system, play a critical role in the global carbon budget. Recent findings have suggested that terrestrial carbon sinks in northern hig...
- Oldest known dinosaurian nesting site and reproductive biology of the Early Jurassic sauropodomorph Massospondylus
[作者:Reisz, RR; Evans, DC; Roberts, EM; Sues, HD; Yates, AM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2428-2433 , 文章类型: Article,,卷期:2012年109-7]
- The extensive Early Jurassic continental strata of southern Africa have yielded an exceptional record of dinosaurs that includes scores of partial to complete skeletons of the sauropodomorph Massospondylus, ranging from ...
- Antibody directs properdin-dependent activation of the complement alternative pathway in a mouse model of abdominal aortic aneurysm
[作者:Zhou, HF; Yan, HM; Stover, CM; Fernandez, TM; de Cordoba, SR; Song, WC; Wu, XB; Thompson, RW; Schwaeble, WJ; Atkinson, JP; Hourcade, DE; Pham, CTN,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:E415-E422 , 文章类型: Article,,卷期:2012年109-7]
- Abdominal aortic aneurysm (AAA) is a complex inflammatory vascular disease. There are currently limited treatment options for AAA when surgery is inapplicable. Therefore, insights into molecular mechanisms underlying AAA...
- Horizontal transfer of chloroplast genomes between plant species
[作者:Stegemann, S; Keuthe, M; Greiner, S; Bock, R,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2434-2438 , 文章类型: Article,,卷期:2012年109-7]
- The genomes of DNA-containing cell organelles (mitochondria, chloroplasts) can be laterally transmitted between organisms, a process known as organelle capture. Organelle capture often occurs in the absence of detectable...
- Cell-to-cell movement of plastids in plants
[作者:Thyssen, G; Svab, Z; Maliga, P,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2439-2443 , 文章类型: Article,,卷期:2012年109-7]
- Our objective was to test whether or not plastids and mitochondria, the two DNA-containing organelles, move between cells in plants. As our experimental approach, we grafted two different species of tobacco, Nicotiana ta...
- Mitochondrial genomes from modern horses reveal the major haplogroups that underwent domestication
[作者:Achilli, A; Olivieri, A; Soares, P; Lancioni, H; Kashani, BH; Perego, UA; Nergadze, SG; Carossa, V; Santagostino, M; Capomaccio, S; Felicetti, M; Al-Achkar, W; Penedo, MCT; Verini-Supplizi, A; Houshmand, M; Woodward, SR; Semino, O; Silvestrelli, M; Giulotto, E; Pereira, L; Bandelt, HJ; Torroni, A,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2449-2454 , 文章类型: Article,,卷期:2012年109-7]
- Archaeological and genetic evidence concerning the time and mode of wild horse (Equus ferus) domestication is still debated. High levels of genetic diversity in horse mtDNA have been detected when analyzing the control r...
- Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair
[作者:Oksenych, V; Alt, FW; Kumar, V; Schwer, B; Wesemann, DR; Hansen, E; Patel, H; Su, A; Guo, CG,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2455-2460 , 文章类型: Article,,卷期:2012年109-7]
- The classical nonhomologous DNA end-joining (C-NHEJ) double-strand break (DSB) repair pathway in mammalian cells maintains genome stability and is required for V(D)J recombination and lymphocyte development. Mutations in...
- Genome-wide siRNA screen for mediators of NF-kappa B activation
[作者:Gewurz, BE; Towfic, F; Mar, JC; Shinners, NP; Takasaki, K; Zhao, B; Cahir-McFarland, ED; Quackenbush, J; Xavier, RJ; Kieff, E,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2467-2472 , 文章类型: Article,,卷期:2012年109-7]
- Although canonical NF kappa B is frequently critical for cell proliferation, survival, or differentiation, NF kappa B hyperactivation can cause malignant, inflammatory, or autoimmune disorders. Despite intensive study, m...
- Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)
[作者:Boboila, C; Oksenych, V; Gostissa, M; Wang, JH; Zha, S; Zhang, Y; Chai, H; Lee, CS; Jankovic, M; Saez, LMA; Nussenzweig, MC; McKinnon, PJ; Alt, FW; Schwer, B,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2473-2478 , 文章类型: Article,,卷期:2012年109-7]
- Classical nonhomologous DNA end-joining (C-NHEJ), which is a major DNA double-strand break (DSB) repair pathway in mammalian cells, plays a dominant role in joining DSBs during Ig heavy chain (IgH) class switch recombina...
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