One-pot and diastereoselective syntheses of diverse chromeno[3,4-c]pyrrole-3,4-diones from readily available starting materials were achieved via sequential Ugi-4CR and intramolecular Michael addition
Several oxidative reactions can be effected with MnO2 in the presence of substoichiometric quantities of DDQ These transformations include oxidative cyclization, deprotection, and dehydrogenation reactions. The use of Mn...
Soluble and stable zethrenebis(dicarboximide) (1) was synthesized by an in situ Stille cross coupling/transannular cyclization reaction 1 showed largely improved photostability and solubility compared with the very unsta...
Chiral nonracemic gamma-seleno-alpha beta-ethylenic esters, when treated with sulfuryl chloride and ethyl vinyl ether in hexanes, produced alpha-chloro-beta,gamma-ethylenic esters in 65-75% yields, with ee values of 95-9...
A blueprint for controlling the stereochemistry of oxygenated 5,5-spiroketals using chelation effects is provided Chelation specifically of zinc salts (other protic and Lewis acids were less effective) between the spirok...
A new, efficient method is developed, based on a palladium(0)-catalyzed reaction of propargylic derivatives with various phosphorus nucleophiles, to produce allenylphosphonates and their analogues with defined stereochem...
The first enantioselective chiral phosphoric acid-catalyzed transfer hydrogenation of unprotected ortho-hydroxyaryl alkyl N-H ketimines using Hantszch di-tert-butyl ester as a reductant is reported. A variety of ortho-hy...