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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共72条记录   Amino Acid Substitutions at Positions 122 and 145 of Hepatitis B Virus Surface Antigen (HBsAg) Determine the Antigenicity and Immunogenicity of HBsAg and Influence In Vivo HBsAg Clearance [作者：Wu, CC; Deng, WY; Deng, L; Cao, L; Qin, B; Li, SX; Wang, Y; Pei, RJ; Yang, DL; Lu, MJ; Chen, XW,期刊：Journal of virology, 页码：4658-4669 , 文章类型： Article，,卷期：2012年86-8] A variety of amino acid substitutions, such as K122I and G145R, have been identified around or within the a determinant of hepatitis B surface antigen (HBsAg), impair HBsAg secretion and antibody binding, and may be resp... Discovery of Retroviral Homologs in Bats: Implications for the Origin of Mammalian Gammaretroviruses [作者：Cui, J; Tachedjian, M; Wang, L; Tachedjian, G; Wang, LF; Zhang, SY,期刊：Journal of virology, 页码：4288-4293 , 文章类型： Article，,卷期：2012年86-8] Gammaretroviruses infect a wide range of vertebrate species where they are associated with leukemias, neurological diseases and immunodeficiencies. However, the origin of these infectious agents is unknown. Through a phy... The Coronavirus Endoribonuclease Nsp15 Interacts with Retinoblastoma Tumor Suppressor Protein [作者：Bhardwaj, K; Liu, PH; Leibowitz, JL; Kao, CC,期刊：Journal of virology, 页码：4294-4304 , 文章类型： Article，,卷期：2012年86-8] Coronaviruses encode an endoribonuclease, Nsp15, which has a poorly defined role in infection. Sequence analysis revealed a retinoblastoma protein-binding motif (LXCXE/D) in the majority of the Nsp15 of the severe acute ... Hepatitis C Virus Induces CD81 and Claudin-1 Endocytosis [作者：Farquhar, MJ; Hu, K; Harris, HJ; Davis, C; Brimacombe, CL; Fletcher, SJ; Baumert, TF; Rappoport, JZ; Balfe, P; McKeating, JA,期刊：Journal of virology, 页码：4305-4316 , 文章类型： Article，,卷期：2012年86-8] Hepatitis C virus (HCV) leads to progressive liver disease and hepatocellular carcinoma. Current treatments are only partially effective, and new therapies targeting viral and host pathways are required. Virus entry into... RNA Synthesis by the Brome Mosaic Virus RNA-Dependent RNA Polymerase in Human Cells Reveals Requirements for De Novo Initiation and Protein-Protein Interaction [作者：Subba-Reddy, CV; Tragesser, B; Xu, ZL; Stein, B; Ranjith-Kumar, CT; Kao, CC,期刊：Journal of virology, 页码：4317-4327 , 文章类型： Article，,卷期：2012年86-8] Brome mosaic virus (BMV) is a model positive-strand RNA virus whose replication has been studied in a number of surrogate hosts. In transiently transfected human cells, the BMV polymerase 2a activated signaling by the in... Disulfide Linkages Mediating Nucleocapsid Protein Dimerization Are Not Required for Porcine Arterivirus Infectivity [作者：Zhang, R; Chen, CY; Sun, Z; Tan, FF; Zhuang, JS; Tian, DB; Tong, GZ; Yuan, SS,期刊：Journal of virology, 页码：4670-4681 , 文章类型： Article，,卷期：2012年86-8] The nucleocapsid (N) proteins of the North American (type II) and European (type I) genotypes of porcine reproductive and respiratory syndrome virus (PRRSV) share only approximately 60% genetic identity, and the function... The Majority of Freshly Sorted Simian Immunodeficiency Virus (SIV)-Specific CD8(+) T Cells Cannot Suppress Viral Replication in SIV-Infected Macrophages [作者：Vojnov, L; Martins, MA; Bean, AT; de Santana, MGV; Sacha, JB; Wilson, NA; Bonaldo, MC; Galler, R; Stevenson, M; Watkins, DI,期刊：Journal of virology, 页码：4682-4687 , 文章类型： Article，,卷期：2012年86-8] Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) primarily infect activated CD4(+) T cells but can infect macrophages. Surprisingly, ex vivo tetramer-sorted SIV-specific CD8(+) T cells that elim... Two Distinct Broadly Neutralizing Antibody Specificities of Different Clonal Lineages in a Single HIV-1-Infected Donor: Implications for Vaccine Design [作者：Bonsignori, M; Montefiori, DC; Wu, XL; Chen, X; Hwang, KK; Tsao, CY; Kozink, DM; Parks, RJ; Tomaras, GD; Crump, JA; Kapiga, SH; Sam, NE; Kwong, PD; Kepler, TB; Liao, HX; Mascola, JR; Haynesa, BF,期刊：Journal of virology, 页码：4688-4692 , 文章类型： Article，,卷期：2012年86-8] Plasma from a small subset of subjects chronically infected with HIV-1 shows remarkable magnitude and breadth of neutralizing activity. From one of these individuals (CH0219), we isolated two broadly neutralizing antibod... Overreliance on the Hexon Gene, Leading to Misclassification of Human Adenoviruses [作者：Singh, G; Robinson, CM; Dehghan, S; Schmidt, T; Seto, D; Jones, MS; Dyer, DW; Chodosh, J,期刊：Journal of virology, 页码：4693-4695 , 文章类型： Article，,卷期：2012年86-8] The genome of human adenovirus (HAdV) D30 was sequenced in depth. Sequence assembly and analysis revealed two distinct viral sequences with identical hexon genes, which were the same as the one previously reported for HA... CRM1-Dependent Trafficking of Retroviral Gag Proteins Revisited [作者：Baluyot, MF; Grosse, SA; Lyddon, TD; Janaka, SK; Johnson, MC,期刊：Journal of virology, 页码：4696-4700 , 文章类型： Article，,卷期：2012年86-8] We analyzed the nuclear trafficking ability of Gag proteins from six retroviral genera. Contrary to a previous report, human immunodeficiency virus type 1 (HIV-1) Gag showed no propensity to cycle through the nucleus. Th... Latency Type-Dependent Modulation of Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Expression by Type I Interferons in B Cells [作者：Salamon, D; Adori, M; Ujvari, D; Wu, L; Kis, LL; Madapura, HS; Nagy, N; Klein, G; Klein, E,期刊：Journal of virology, 页码：4701-4707 , 文章类型： Article，,卷期：2012年86-8] We report that type I interferons (IFNs) upregulate latent membrane protein 1 (LMP-1) expression by direct activation of the ED-L1 promoter in several Epstein-Barr virus (EBV)-carrying Burkitt's lymphoma lines. In EBV-in... Discovery of Potential Diagnostic and Vaccine Antigens in Herpes Simplex Virus 1 and 2 by Proteome-Wide Antibody Profiling [作者：Kalantari-Dehaghi, M; Chun, S; Chentoufi, AA; Pablo, J; Liang, L; Dasgupta, G; Molina, DM; Jasinskas, A; Nakajima-Sasaki, R; Felgner, J; Hermanson, G; BenMohamed, L; Felgner, PL; Davies, DH,期刊：Journal of virology, 页码：4328-4339 , 文章类型： Article，,卷期：2012年86-8] Routine serodiagnosis of herpes simplex virus (HSV) infections is currently performed using recombinant glycoprotein G (gG) antigens from herpes simplex virus 1 (HSV-1) and HSV-2. This is a single-antigen test and has on... Tiled Microarray Identification of Novel Viral Transcript Structures and Distinct Transcriptional Profiles during Two Modes of Productive Murine Gammaherpesvirus 68 Infection [作者：Cheng, BYH; Zhi, JZ; Santana, A; Khan, S; Salinas, E; Forrest, JC; Zheng, YT; Jaggi, S; Leatherwood, J; Krug, LT,期刊：Journal of virology, 页码：4340-4357 , 文章类型： Article，,卷期：2012年86-8] We applied a custom tiled microarray to examine murine gammaherpesvirus 68 (MHV68) polyadenylated transcript expression in a time course of de novo infection of fibroblast cells and following phorbol ester-mediated react... Immunodominant "Asymptomatic" Herpes Simplex Virus 1 and 2 Protein Antigens Identified by Probing Whole-ORFome Microarrays with Serum Antibodies from Seropositive Asymptomatic versus Symptomatic Individuals [作者：Dasgupta, G; Chentoufi, AA; Kalantari, M; Falatoonzadeh, P; Chun, S; Lim, CH; Felgner, PL; Davies, DH; BenMohamed, L,期刊：Journal of virology, 页码：4358-4369 , 文章类型： Article，,卷期：2012年86-8] Herpes simplex virus 1 (HSV-1) and HSV-2 are medically significant pathogens. The development of an effective HSV vaccine remains a global public health priority. HSV-1 and HSV-2 immunodominant "asymptomatic" antigens (I... Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection [作者：Ambrose, Z; Lee, K; Ndjomou, J; Xu, HZ; Oztop, I; Matous, J; Takemura, T; Unutmaz, D; Engelman, A; Hughes, SH; KewalRamani, VN,期刊：Journal of virology, 页码：4708-4714 , 文章类型： Article，,卷期：2012年86-8] The antiviral factor CPSF6-358 interferes with the nuclear entry of human immunodeficiency virus type 1 (HIV-1). HIV-1 acquires resistance to CPSF6-358 through the N74D mutation of the capsid (CA), which alters its nucle... Full Genomic Sequence of the Prototype Strain (M64) of Rio Bravo Virus [作者：Volkova, E; Tesh, RB; Monath, TP; Vasilakis, N,期刊：Journal of virology, 页码：4715-4715 , 文章类型： Article，,卷期：2012年86-8] Rio Bravo virus (RBV) is a member of the family Flaviviridae, genus Flavivirus. It belongs to a group of viruses in the genus with no known vector. In this report, we analyze the complete genome of the prototype RBV, str...