- Genome-wide Repression of NF-kappa B Target Genes by Transcription Factor MIBP1 and Its Modulation by O-Linked beta-N-Acetylglucosamine (O-GlcNAc) Transferase
[作者:Iwashita, Y; Fukuchi, N; Waki, M; Hayashi, K; Tahira, T,期刊:Journal of Biological Chemistry, 页码:9887-9900 , 文章类型: Article,,卷期:2012年287-13]
- The transcription factor c-MYC intron binding protein 1 (MIBP1) binds to various genomic regulatory regions, including intron 1 of c-MYC. This factor is highly expressed in postmitotic neurons in the fetal brain and may ...
- Mutations in N-terminal Flanking Region of Blue Light-sensing Light-Oxygen and Voltage 2 (LOV2) Domain Disrupt Its Repressive Activity on Kinase Domain in the Chlamydomonas Phototropin
[作者:Aihara, Y; Yamamoto, T; Okajima, K; Yamamoto, K; Suzuki, T; Tokutomi, S; Tanaka, K; Nagatani, A,期刊:Journal of Biological Chemistry, 页码:9901-9909 , 文章类型: Article,,卷期:2012年287-13]
- Phototropin is a light-regulated kinase that mediates a variety of photoresponses such as phototropism, chloroplast positioning, and stomata opening in plants to increase the photosynthetic efficiency. Blue light stimulu...
- alpha-Enolase of Streptococcus pneumoniae Induces Formation of Neutrophil Extracellular Traps
[作者:Mori, Y; Yamaguchi, M; Terao, Y; Hamada, S; Ooshima, T; Kawabata, S,期刊:Journal of Biological Chemistry, 页码:10472-10481 , 文章类型: Article,,卷期:2012年287-13]
- Streptococcus pneumoniae is the most common causative agent of community-acquired pneumonia throughout the world, with high morbidity and mortality rates. A major feature of pneumococcal pneumonia is abundant neutrophil ...
- MicroRNA Profile of Circulating CD4-positive Regulatory T Cells in Human Adults and Impact of Differentially Expressed MicroRNAs on Expression of Two Genes Essential to Their Function
[作者:Fayyad-Kazan, H; Rouas, R; Fayyad-Kazan, M; Badran, R; El Zein, N; Lewalle, P; Najar, M; Hamade, E; Jebbawi, F; Merimi, M; Romero, P; Burny, A; Badran, B; Martiat, P,期刊:Journal of Biological Chemistry, 页码:9910-9922 , 文章类型: Article,,卷期:2012年287-13]
- Regulatory T cells (Tregs) are characterized by a high expression of IL-2 receptor alpha chain (CD25) and of forkhead box P3 (FOXP3), the latter being essential for their development and function. Another major player in...
- Human Primary Keratinocytes Show Restricted Ability to Up-regulate Suppressor of Cytokine Signaling (SOCS)3 Protein Compared with Autologous Macrophages
[作者:Zeitvogel, J; Dalpke, A; Eiz-Vesper, B; Kracht, M; Dittrich-Breiholz, O; Werfel, T; Wittmann, M,期刊:Journal of Biological Chemistry, 页码:9923-9930 , 文章类型: Article,,卷期:2012年287-13]
- Suppressor of cytokine signaling (SOCS)3 belongs to a family of proteins that are known to exert important functions as inducible feedback inhibitors and are crucial for the balance of immune responses. There is evidence...
- Regulation of a Proteinaceous Elicitor-induced Ca2+ Influx and Production of Phytoalexins by a Putative Voltage-gated Cation Channel, OsTPC1, in Cultured Rice Cells
[作者:Hamada, H; Kurusu, T; Okuma, E; Nokajima, H; Kiyoduka, M; Koyano, T; Sugiyama, Y; Okada, K; Koga, J; Saji, H; Miyao, A; Hirochika, H; Yamane, H; Murata, Y; Kuchitsu, K,期刊:Journal of Biological Chemistry, 页码:9931-9939 , 文章类型: Article,,卷期:2012年287-13]
- Pathogen/microbe-or plant-derived signaling molecules (PAMPs/MAMPs/DAMPs) or elicitors induce increases in the cytosolic concentration of free Ca2+ followed by a series of defense responses including biosynthesis of anti...
- Bacterial Degradation of Benzoate CROSS-REGULATION BETWEEN AEROBIC AND ANAEROBIC PATHWAYS
[作者:Valderrama, JA; Durante-Rodriguez, G; Blazquez, B; Garcia, JL; Carmona, M; Diaz, E,期刊:Journal of Biological Chemistry, 页码:10494-10508 , 文章类型: Article,,卷期:2012年287-13]
- We have studied for the first time the transcriptional regulatory circuit that controls the expression of the box genes encoding the aerobic hybrid pathway used to assimilate benzoate via coenzyme A (CoA) derivatives in ...
- Hypermethylated in Cancer 1 (HIC1) Recruits Polycomb Repressive Complex 2 (PRC2) to a Subset of Its Target Genes through Interaction with Human Polycomb-like (hPCL) Proteins
[作者:Boulay, G; Dubuissez, M; Van Rechem, C; Forget, A; Helin, K; Ayrault, O; Leprince, D,期刊:Journal of Biological Chemistry, 页码:10509-10524 , 文章类型: Article,,卷期:2012年287-13]
- HIC1 (hypermethylated in cancer 1) is a tumor suppressor gene epigenetically silenced or deleted in many human cancers. HIC1 is involved in regulatory loops modulating p53- and E2F1-dependent cell survival, growth contro...
- Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid
[作者:Isobe, Y; Arita, M; Matsueda, S; Iwamoto, R; Fujihara, T; Nakanishi, H; Taguchi, R; Masuda, K; Sasaki, K; Urabe, D; Inoue, M; Arai, H,期刊:Journal of Biological Chemistry, 页码:10525-10534 , 文章类型: Article,,卷期:2012年287-13]
- Bioactive mediators derived from omega-3 eicosapentaenoic acid (EPA) elicit potent anti-inflammatory actions. Here, we identified novel EPA metabolites, including 8,18-dihydroxyei-cosapentaenoic acid (8,18-diHEPE), 11,18...
- Constitutive Production of Catalytic Antibodies to a Staphylococcus aureus Virulence Factor and Effect of Infection
[作者:Brown, EL; Nishiyama, Y; Dunkle, JW; Aggarwal, S; Planque, S; Watanabe, K; Csencsits-Smith, K; Bowden, MG; Kaplan, SL; Paul, S,期刊:Journal of Biological Chemistry, 页码:9940-9951 , 文章类型: Article,,卷期:2012年287-13]
- Antibodies that recognize microbial B lymphocyte superantigenic epitopes are produced constitutively with no requirement for adaptive immune maturation. We report cleavage of the Staphylococcus aureus virulence factor ex...
- Heparan Sulfate Chains of Syndecan-1 Regulate Ectodomain Shedding
[作者:Ramani, VC; Pruett, PS; Thompson, CA; DeLucas, LD; Sanderson, RD,期刊:Journal of Biological Chemistry, 页码:9952-9961 , 文章类型: Article,,卷期:2012年287-13]
- Matrix metalloproteinases release intact syndecan-1 ectodomains from the cell surface giving rise to a soluble, shed form of the proteoglycan. Although it is known that shed syndecan-1 controls diverse pathophysiological...
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