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  • Sequential Regulation of DOCK2 Dynamics by Two Phospholipids During Neutrophil Chemotaxis
    [作者:Nishikimi, A; Fukuhara, H; Su, WJ; Hongu, T; Takasuga, S; Mihara, H; Cao, QH; Sanematsu, F; Kanai, M; Hasegawa, H; Tanaka, Y; Shibasaki, M; Kanaho, Y; Sasaki, T; Frohman, MA; Fukui, Y,期刊:Science, 页码:384-387 , 文章类型: Article,,卷期:2009年324-5925]
  • During chemotaxis, activation of the small guanosine triphosphatase Rac is spatially regulated to organize the extension of membrane protrusions in the direction of migration. In neutrophils, Rac activation is primarily ...
  • Geometric frustration in buckled colloidal monolayers
    [作者:Han, Yilong; Shokef, Yair; Alsayed, Ahmed M.; Yunker, Peter; Lubensky, Tom C.; Yodh, Arjun G.,期刊:NATURE, 页码:898-903 , 文章类型: 研究论文,,卷期:2008年456-7224]
  • Geometric frustration arises when lattice structure prevents simultaneous minimization of local interaction energies. It leads to highly degenerate ground states and, subsequently, to complex phases of matter, such as wa...
  • Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation
    [作者:Kang, Rujun; Wan, Junmei; Arstikaitis, Pamela; Takahashi, Hideto; Huang, Kun; Bailey, Aaron O.; Thompson, James X.; Roth, Amy F.; Drisdel, Renaldo C.; Mastro, Ryan; Green, William N.; Yates, John R., III; Davis, Nicholas G.; El-Husseini, Alaa,期刊:NATURE, 页码:904-909 , 文章类型: 研究论文,,卷期:2008年456-7224]
  • Palmitoylation regulates diverse aspects of neuronal protein trafficking and function. Here a global characterization of rat neural palmitoyl- proteomes identifies most of the known neural palmitoyl proteins - 68 in tota...
  • Acylated Iridoids with Cytotoxicity from Valeriana jatamansi
    [作者:Lin, S; Shen, YH; Li, HL; Yang, XW; Chen, T; Lu, LH; Huang, ZS; Liu, RH; Xu, XK; Zhang, WD; Wang, H,期刊:Journal of natural products, 页码:650-655 , 文章类型: Article,,卷期:2009年72-4]
  • Thirteen new acylated iridoids, jatamanvaltrates A-M (1-13), together with nine known valepotriates (14-22), were isolated from the whole plants of Valeriana jatamansi (syn. Valeriana wallichii). The structures of these ...
  • Spliceosomal cleavage generates the 3 ' end of telomerase RNA
    [作者:Box, Jessica A.; Bunch, Jeremy T.; Tang, Wen; Baumann, Peter,期刊:NATURE, 页码:910-U71 , 文章类型: 研究论文,,卷期:2008年456-7224]
  • Telomeres cap the ends of chromosomes and provide a means to complete replication. The DNA portion of telomeres is synthesized by the enzyme telomerase using part of an RNA subunit as a template for reverse transcription...
  • Antigenic variation in Giardia lamblia is regulated by RNA interference
    [作者:Prucca, Cesar G.; Slavin, Ileana; Quiroga, Rodrigo; Elias, Eliana V.; Rivero, Fernando D.; Saura, Alicia; Carranza, Pedro G.; Lujan, Hugo D.,期刊:NATURE, 页码:750-754 , 文章类型: 研究论文,,卷期:2008年456-7223]
  • Giardia lamblia ( also called Giardia intestinalis) is one of the most common intestinal parasites of humans. To evade the host's immune response, Giardia undergoes antigenic variation - a process that allows the parasit...
  • Semisynthesis and Biological Activity of Stemofoline Alkaloids
    [作者:Baird, MC; Pyne, SG; Ung, AT; Lie, W; Sastraruji, T; Jatisatienr, A; Jatisatienr, C; Dheeranupattana, S; Lowlam, J; Boonchalermkit, S,期刊:Journal of natural products, 页码:679-684 , 文章类型: Article,,卷期:2009年72-4]
  • The semisynthesis of the Stemona alkaloids (3'R)-stemofolenol (1). (3'S)-stemofolenol (2), methylstemofoline (3), and (3'S)-hydroxystemofoline (5) and the unnatural analogues (11E)-methylstemofoline (15) and 3'R-hydroxys...
  • Negative feedback that improves information transmission in yeast signalling
    [作者:Yu, Richard C.; Pesce, C. Gustavo; Colman-Lerner, Alejandro; Lok, Larry; Pincus, David; Serra, Eduard; Holl, Mark; Benjamin, Kirsten; Gordon, Andrew; Brent, Roger,期刊:NATURE, 页码:755-761 , 文章类型: 研究论文,,卷期:2008年456-7223]
  • Haploid Saccharomyces cerevisiae yeast cells use a prototypic cell signalling system to transmit information about the extracellular concentration of mating pheromone secreted by potential mating partners. The ability of...
  • Terpenoids from Toona ciliata
    [作者:Chen, HD; Yang, SP; Wu, Y; Dong, L; Yue, JM,期刊:Journal of natural products, 页码:685-689 , 文章类型: Article,,卷期:2009年72-4]
  • Three new norlimonoids (1-3), two new tirucallane-type triterpenoids (4 and 5), and a new pimaradiene-type diterpenoid (6), along with two known limonoids and eight known tirucallane-type triterpenoids, were isolated fro...