Five Pt(II) complexes were tested for their ability to interfere in Cu(II) or Zn(II) coordination to the A beta peptide. Two of them induce modifications of the Cu(II) sphere but not the associated Cu(A beta) ROS product...
A molecular beacon (MB)-like DNA hairpin biosensor based on the reversible directing fluorescence of Hoechst dyes was developed for fluorescent detection of Hg2+ and biothiols and furthermore for logic operation.
Sphingosine kinase isoform 1 (SK1) inhibitors may serve as therapeutic agents for proliferative diseases, including hypertension. We synthesized a series of sphingosine-based SK1-selective inhibitors, the most potent of ...
Novel pH sensors relying on 1-aminoperylene bisimide dyes covalently grafted onto cross-linked poly(acryloylmorpholine) are presented. They feature fluorescence in the near infra-red range and a large Stokes shift (>90 n...
Here we report a covalent bonding approach to fabricate a robust metal-organic framework ZIF-90 coating for solid-phase microextraction. The ZIF-90 bonded fiber exhibits high enhancement factors, wide linearity, excellen...
Thermal Bergman cyclization of Pt(II) dialkynylporphyrins reveals a marked reduction in the cyclization temperature relative to the free base and Zn(II) derivatives. In contrast, photogenerated (3)pi pi* population produ...
A paramagnetic Sc3NC@C-80 anion radical was obtained by chemical reduction. ESR spectrometry and theoretical calculations disclosed that the core NC moiety takes possession of the unpaired electron and stabilizes the par...
No-carrier-added [F-18]fluoroarenes were synthesized through the radiofluorination of diaryl sulfoxides with [F-18]fluoride ion. Diaryl sulfoxides bearing a para electron-withdrawing substituent readily gave the correspo...
An efficient and operationally simple synthesis of fluoroalkanes by deoxygenative hydrofluorination of carbonyl compounds via their tosylhydrazone surrogates is reported. The reaction can be carried out in a one-pot proc...
Aminocatalyzed asymmetric Diels-Alder reaction between 2,4-dienals and rhodanine/hydantoin derivatives via trienamine mechanism has been developed to synthesize various spirocyclic compounds with good yields (up to 98%) ...
Polymers that start degrading under acidic conditions are increasingly investigated as a pathway to trigger the release of drugs once the drug carrier reached the slightly acidic tumour environment or after the drug carr...
The bonding in the unbridged closed-shell Au(II)-Au(II) dimers X4Au2(C5H5N)(2), X = H, F-I and CF3, is analyzed and the short Au-Au bonds around 250 pm are reproduced by a novel 6s6p(z)5d(xy) hybridization.
A novel ferrocenyl-terminated dendrimer with an electron-relay framework was designed as an efficient tracing tag to quench the cathodic electrochemiluminescence emission of quantum dots, which led to a dual quenching ef...
Amide-linked tripyridine derivatives 1, with a para-substituent, and 2, with a meta-substituent, were gelated in water or water-DMSO. The gelation capabilities of 1 and 2 were attributed to the cooperative effects of mai...
The multitopic ion-pair receptor 2 is able to recognize and extract various cesium and potassium salts via three different ion recognition modes. Furthermore, it is capable of extracting and then releasing KNO3 via ion-p...
We developed supramolecular hydrogels exhibiting reversible thermochromism concurrently with gel-to-sol transition from four glycolipids. In addition, these gels showed the similar color change in response to glycosidase...