- Protection Against Staphylococcus aureus by Antibody to the Polyglycerolphosphate Backbone of Heterologous Lipoteichoic Acid
[作者:Theilacker, C; Kropec, A; Hammer, F; Sava, I; Wobser, D; Sakinc, T; Codee, JDC; Hogendorf, WFJ; van der Marel, GA; Huebner, J,期刊:Journal of Infectious Diseases, 页码:1076-1085 , 文章类型: Article,,卷期:2012年205-7]
- Type 1 lipoteichoic acid (LTA) is present in many clinically important gram-positive bacteria, including enterococci, streptococci, and staphylococci, and antibodies against LTA have been shown to opsonize nonencapsulate...
- CpG Methylation as a Tool to Characterize Cell-Free Kaposi Sarcoma Herpesvirus DNA
[作者:Shamay, M; Hand, N; Lemas, MV; Koon, HB; Krown, SE; Wrangle, J; Desai, P; Ramos, JC; Ambinder, RF,期刊:Journal of Infectious Diseases, 页码:1095-1099 , 文章类型: Article,,卷期:2012年205-7]
- We studied the presence of Kaposi sarcoma herpesvirus sequences in cell-free DNA (cfDNA) isolated from the blood of patients with AIDS-related Kaposi sarcoma (KS) and primary effusion lymphoma (PEL). The use of paramagne...
- Defective Monocyte Dynamics in Q Fever Granuloma Deficiency
[作者:Delaby, A; Gorvel, L; Espinosa, L; Lepolard, C; Raoult, D; Ghigo, E; Capo, C; Mege, JL,期刊:Journal of Infectious Diseases, 页码:1086-1094 , 文章类型: Article,,卷期:2012年205-7]
- Background. The outcome of Q fever, an infectious disease caused by Coxiella burnetii, is associated with granuloma formation. Granulomas are present in patients with resolutive Q fever but are lacking in patients with c...
- Ribavirin Regulates Hepatitis C Virus Replication Through Enhancing Interferon-Stimulated Genes and Interleukin 8
[作者:Tokumoto, Y; Hiasa, Y; Uesugi, K; Watanabe, T; Mashiba, T; Abe, M; Kumagi, T; Ikeda, Y; Matsuura, B; Onji, M,期刊:Journal of Infectious Diseases, 页码:1121-1130 , 文章类型: Article,,卷期:2012年205-7]
- Background. The manner in which ribavirin (RBV) enhances the antiviral effects of interferon (IFN) against hepatitis C virus (HCV) remains unknown. We investigated whether RBV modifies IFN-stimulated genes (ISGs) in vivo...
- Differential Antigen Specificity of Hepatitis C Virus-Specific Interleukin 17-and Interferon gamma-Producing CD8+ T Cells During Chronic Infection
[作者:Grafmueller, S; Billerbeck, E; Blum, HE; Neumann-Haefelin, C; Thimme, R,期刊:Journal of Infectious Diseases, 页码:1142-1146 , 文章类型: Article,,卷期:2012年205-7]
- A subset of CD8+ T cells can secrete interleukin 17 (IL-17). However, very little information is currently available about their antigen specificity, tissue distribution, and biological relevance in chronic human viral i...
- Dissection of a Circulating and Intrahepatic CD4(+)Foxp3(+) T-Cell Subpopulation in Chronic Hepatitis B Virus (HBV) Infection: A Highly Informative Strategy for Distinguishing Chronic HBV Infection States
[作者:Zhang, MJ; Zhou, JJ; Zhao, TT; Huang, GY; Tan, YL; Tan, S; Fu, XL; Niu, W; Meng, G; Chen, XL; Shang, XY; Liu, D; Ni, B; Wang, L; Wu, YZ,期刊:Journal of Infectious Diseases, 页码:1111-1120 , 文章类型: Article,,卷期:2012年205-7]
- Background. The definition of CD4(+)Foxp3(+) regulatory T cells (Tregs) is challenging as it relates to chronic hepatitis B virus (HBV) infection. Recently, the heterogeneity of human CD4(+)Foxp3(+) T cells has been conf...
- Secretome of Human Bronchial Epithelial Cells in Response to the Fungal Pathogen Aspergillus fumigatus Analyzed by Differential In-Gel Electrophoresis
[作者:Fekkar, A; Balloy, V; Pionneau, C; Marinach-Patrice, C; Chignard, M; Mazier, D,期刊:Journal of Infectious Diseases, 页码:1163-1172 , 文章类型: Article,,卷期:2012年205-7]
- Background. For years, the analysis of innate responses to the major mold pathogen Aspergillus fumigatus has been restricted to specialized cells, such as professional phagocytes. More recently, the contribution of the a...
- Intravenous Ferric Carboxymaltose Accelerates Erythropoietic Recovery From Experimental Malarial Anemia
[作者:Maretty, L; Sharp, RE; Andersson, M; Kurtzhals, JAL,期刊:Journal of Infectious Diseases, 页码:1173-1177 , 文章类型: Article,,卷期:2012年205-7]
- Iron restriction has been proposed as a cause of erythropoietic suppression in malarial anemia; however, the role of iron in malaria remains controversial, because it may increase parasitemia. To investigate the role of ...
- Early Appearance of Neutralizing Immunoglobulin G3 Antibodies Is Associated With Chikungunya Virus Clearance and Long-term Clinical Protection
[作者:Kam, YW; Simarmata, D; Chow, A; Her, Z; Teng, TS; Ong, EKS; Renia, L; Leo, YS; Ng, LFP,期刊:Journal of Infectious Diseases, 页码:1147-1154 , 文章类型: Article,,卷期:2012年205-7]
- Background. Chikungunya virus (CHIKV) and related arboviruses have been responsible for large epidemic outbreaks with serious economic and social impact. Although infected individuals clear the virus from the blood, some...
- Multicohort Genomewide Association Study Reveals a New Signal of Protection Against HIV-1 Acquisition
[作者:Limou, S; Delaneau, O; van Manen, D; An, P; Sezgin, E; Le Clerc, S; Coulonges, C; Troyer, JL; Veldink, JH; van den Berg, LH; Spadoni, JL; Taing, L; Labib, T; Montes, M; Delfraissy, JF; Schachter, F; O'Brien, SJ; Buchbinder, S; van Natta, ML; Jabs, DA; Froguel, P; Schuitemaker, H; Winkler, CA; Zagury, JF,期刊:Journal of Infectious Diseases, 页码:1155-1162 , 文章类型: Article,,卷期:2012年205-7]
- Background. To date, onlymutations in CCR5 have been shown to confer resistance to human immunodeficiency virus type 1 (HIV-1) infection, and these explain only a small fraction of the observed variability in HIV suscept...
- Nasopharyngeal Microbiota in Infants With Acute Otitis Media
[作者:Hilty, M; Qi, WH; Brugger, SD; Frei, L; Agyeman, P; Frey, PM; Aebi, S; Muhlemann, K,期刊:Journal of Infectious Diseases, 页码:1048-1055 , 文章类型: Article,,卷期:2012年205-7]
- Background. Interspecies interactions of the nasopharyngeal microbiota are likely to be involved in the pathogenesis of acute otitis media (AOM). Capturing the breadth of microbial interactions requires a detailed descri...
- A Human Challenge Model for Mycobacterium tuberculosis Using Mycobacterium bovis Bacille Calmette-Guerin
[作者:Minassian, AM; Satti, I; Poulton, ID; Meyer, J; Hill, AVS; McShane, H,期刊:Journal of Infectious Diseases, 页码:1035-1042 , 文章类型: Article,,卷期:2012年205-7]
- Background. There is currently no safe human challenge model of Mycobacterium tuberculosis infection to enable proof-of-concept efficacy evaluation of candidate vaccines against tuberculosis. In vivo antimycobacterial im...
- ASP2151 for the Treatment of Genital Herpes: A Randomized, Double-Blind, Placebo- and Valacyclovir-Controlled, Dose-Finding Study
[作者:Tyring, S; Wald, A; Zadeikis, N; Dhadda, S; Takenouchi, K; Rorig, R,期刊:Journal of Infectious Diseases, 页码:1100-1110 , 文章类型: Article,,卷期:2012年205-7]
- Background. Current therapies for genital herpes have only partial efficacy. Helicase-primase inhibitors are novel, potent inhibitors of herpes simplex virus replication. Methods. This randomized trial assessed the safet...
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