- Bone regeneration mediated by biomimetic mineralization of a nanofiber matrix
[作者:Mata, A; Geng, YB; Henrikson, KJ; Aparicio, C; Stock, SR; Satcher, RL; Stupp, SI,期刊:BIOMATERIALS, 页码:6004-6012 , 文章类型: Article,,卷期:2010年31-23]
- Rapid bone regeneration within a three-dimensional defect without the use of bone grafts, exogenous growth factors, or cells remains a major challenge. We report here on the use of self-assembling peptide nanostructured ...
- SiRNA-loaded multi-shell nanoparticles incorporated into a multilayered film as a reservoir for gene silencing
[作者:Zhang, X; Kovtun, A; Mendoza-Palomares, C; Oulad-Abdelghani, M; Fioretti, F; Rinckenbach, S; Mainard, D; Epple, M; Benkirane-Jessel, N,期刊:BIOMATERIALS, 页码:6013-6018 , 文章类型: Article,,卷期:2010年31-23]
- In this study, we presented a new type of coating based on polyelectrolyte multilayers containing sequentially adsorbed active shRNA calcium phosphate nanoparticles for locally defined and temporarily variable gene silen...
- The effectiveness of the controlled release of gentamicin from polyelectrolyte multilayers in the treatment of Staphylococcus aureus infection in a rabbit bone model
[作者:Moskowitz, JS; Blaisse, MR; Samuel, RE; Hsu, HP; Harris, MB; Martin, SD; Lee, JC; Spector, M; Hammond, PT,期刊:BIOMATERIALS, 页码:6019-6030 , 文章类型: Article,,卷期:2010年31-23]
- While the infection rate of orthopedic implants is low, the required treatment, which can involve six weeks of antibiotic therapy and two additional surgical operations, is life threatening and expensive, and thus motiva...
- Tyrosine-based rivastigmine-loaded organogels in the treatment of Alzheimer's disease
[作者:Bastiat, G; Plourde, F; Motulsky, A; Furtos, A; Dumont, Y; Quirion, R; Fuhrmann, G; Leroux, JC,期刊:BIOMATERIALS, 页码:6031-6038 , 文章类型: Article,,卷期:2010年31-23]
- Organogels can be prepared by immobilizing an organic phase into a three-dimensional network coming from the self-assembly of a low molecular weight gelator molecule. In this work, an injectable subcutaneous organogel sy...
- Live cell-based sensor cells
[作者:Taniguchi, A,期刊:BIOMATERIALS, 页码:5911-5915 , 文章类型: Article,,卷期:2010年31-23]
- Biosensors utilizing live cells have attracted a great deal of attention because of their high specificity and sensitivity to their targets. We established cytotoxic sensor cells that were transfected with GET plasmids d...
- The development of electrically conductive polycaprolactone fumarate-polypyrrole composite materials for nerve regeneration
[作者:Runge, MB; Dadsetan, M; Baltrusaitis, J; Knight, AM; Ruesink, T; Lazcano, EA; Lu, LC; Windebank, AJ; Yaszemski, MJ,期刊:BIOMATERIALS, 页码:5916-5926 , 文章类型: Article,,卷期:2010年31-23]
- Electrically conductive polymer composites composed of polycaprolactone fumarate and polypyrrole (PCLF-PPy) have been developed for nerve regeneration applications. Here we report the synthesis and characterization of PC...
- Biomimetic hybrid scaffolds for engineering human tooth-ligament interfaces
[作者:Park, CH; Rios, HF; Jin, QM; Bland, ME; Flanagan, CL; Hollister, SJ; Giannobile, WV,期刊:BIOMATERIALS, 页码:5945-5952 , 文章类型: Article,,卷期:2010年31-23]
- A major clinical challenge in the reconstruction of large oral and craniofacial defects is the neogenesis of osseous and ligamentous interfacial structures. Currently, oral regenerative medicine strategies are unpredicta...
- Autophagy and oxidative stress associated with gold nanoparticles
[作者:Li, JJ; Hartono, D; Ong, CN; Bay, BH; Yung, LYL,期刊:BIOMATERIALS, 页码:5996-6003 , 文章类型: Article,,卷期:2010年31-23]
- Elemental metal nanoparticles like cadmium and silver are known to cause oxidative stress and are also highly toxic. Yet for gold nanoparticles (AuNPs), it is not well established whether these particles are biologically...
- Cultivating hepatocytes on printed arrays of HGF and BMP7 to characterize protective effects of these growth factors during in vitro alcohol injury
[作者:Jones, CN; Tuleuova, N; Lee, JY; Ramanculov, E; Reddi, AH; Zern, MA; Revzin, A,期刊:BIOMATERIALS, 页码:5936-5944 , 文章类型: Article,,卷期:2010年31-23]
- The goal of the present study was to investigate hepato-protective effects of growth factor (CF) arrays during alcohol injury. Hepatocyte growth factor (HGF) and bone morphogenetic protein (BMP)7 were mixed with collagen...
- The use of superporous Ac-CGGASIKVAVS-OH-modified PHEMA scaffolds to promote cell adhesion and the differentiation of human fetal neural precursors
[作者:Kubinova, S; Horak, D; Kozubenko, N; Vanecek, V; Proks, V; Price, J; Cocks, G; Sykova, E,期刊:BIOMATERIALS, 页码:5966-5975 , 文章类型: Article,,卷期:2010年31-23]
- Modifications of poly(2-hydroxyethyl methacrylate) (PHEMA) with laminin-derived Ac-CGGASIKVAVS-OH peptide sequences have been developed to construct scaffolds that promote cell adhesion and neural differentiation. Radica...
- In vivo restoration of full-thickness cartilage defects by poly(lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes
[作者:Wang, W; Li, B; Li, YL; Jiang, YZ; Ouyang, HW; Gao, CY,期刊:BIOMATERIALS, 页码:5953-5965 , 文章类型: Article,,卷期:2010年31-23]
- A composite construct comprising of bone marrow mesenchymal stem cells (BMSCs), plasmid DNA encoding transforming growth factor-beta 1 (pDNA-TGF-beta 1), fibrin gel and poly (lactide-co-glycolide) (PLGA) sponge was desig...
- Artificial oxygen carrier based on polysaccharides-poly(alkylcyanoacrylates) nanoparticle templates
[作者:Chauvierre, C; Manchanda, R; Labarre, D; Vauthier, C; Marden, MC; Leclerc, L,期刊:BIOMATERIALS, 页码:6069-6074 , 文章类型: Article,,卷期:2010年31-23]
- Biomimetic nanoparticles based on polysaccharides-poly(alkylcyanoacrylates) copolymers were initially developed in view of drug delivery. Core-shell nanoparticles covered with a sufficiently long brush of polysaccharides...
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