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  • Methylation-dependent DNA restriction in Bacillus anthracis
    [作者:Sitaraman, R; Leppla, SH,期刊:Gene, 页码:44-50 , 文章类型: Article,,卷期:2012年494-1]
  • Bacillus anthracis, the causative agent of anthrax, is poorly transformed with DNA that is methylated on adenine or cytosine. Here we characterize three genetic loci encoding type IV methylation-dependent restriction enz...
  • TLR1 polymorphisms in Europeans and spontaneous pregnancy loss
    [作者:Crisan, TO; Farcas, MF; Trifa, AP; Plantinga, TS; Militaru, MS; Pop, IV; Netea, MG; Popp, RA,期刊:Gene, 页码:109-111 , 文章类型: Article,,卷期:2012年494-1]
  • Toll-like receptors (TLRs) are critical components of the pathogen recognition by the host innate immune system. Recently it has been shown that TLR1 is under evolutionary pressure in Europeans. This involves the positiv...