- The trafficking proteins Vacuolar Protein Sorting 35 and Neurobeachin interact with the glycine receptor beta-subunit
[作者:del Pino, I; Paarmann, I; Karas, M; Kilimann, MW; Betz, H,期刊:Biochemical and Biophysical Research Communications, 页码:435-440 , 文章类型: Article,,卷期:2011年412-3]
- Inhibitory glycine receptors (GlyRs) are densely packed in the postsynaptic membrane due to a high-affinity interaction of their beta-subunits with the scaffolding protein gephyrin. Here, we used an affinity-based proteo...
- Nuclear translocation of phosphorylated STAT3 regulates VEGF-A-induced lymphatic endothelial cell migration and tube formation
[作者:Okazaki, H; Tokumaru, S; Hanakawa, Y; Shiraishi, K; Shirakata, Y; Dai, XJ; Yang, LJ; Tohyama, M; Hashimoto, K; Sayama, K,期刊:Biochemical and Biophysical Research Communications, 页码:441-445 , 文章类型: Article,,卷期:2011年412-3]
- Vascular endothelial growth factor (VEGF) is an endothelial cell-specific growth factor that regulates endothelial functions, and signal transducers and activators of transcription (STATs) are known to be important durin...
- Global functional knockdown of ATP binding cassette transporter A1 stimulates development of atherosclerosis in apoE K/O mice
[作者:Mukhamedova, N; D'Souza, W; Low, H; Kesani, R; Chimini, G; Sviridov, D,期刊:Biochemical and Biophysical Research Communications, 页码:446-449 , 文章类型: Article,,卷期:2011年412-3]
- ABCA1 is a key element of cellular cholesterol homeostasis. ApoE K/O mice fed with high-fat diet were infused with anti-ABCA1 antibody or control IgM. Infusion of anti-ABCA1 antibody led to 72% increase in the area of at...
- Polymorphism G861C of 5-HT receptor subtype 1B is associated with heroin dependence in Han Chinese
[作者:Gao, F; Zhu, YS; Wei, SG; Li, SB; Lai, JH,期刊:Biochemical and Biophysical Research Communications, 页码:450-453 , 文章类型: Article,,卷期:2011年412-3]
- The serotoninergic (5-HT) system regulates neuronal activity in broad brain regions, and appears to be particularly important for modulating behavioral and physiological functions such as mood, emotion, sleep and appetit...
- A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration
[作者:Jin, HS; Park, HS; Shin, JH; Kim, DH; Jun, SH; Lee, CJ; Lee, TH,期刊:Biochemical and Biophysical Research Communications, 页码:454-459 , 文章类型: Article,,卷期:2011年412-3]
- The inhibitors of apoptosis proteins (IAP), which include cIAP1, cIAP2 and XIAP, suppress apoptosis through the inhibition of caspases, and the activity of IAPs is regulated by a variety of IAP-binding proteins. Herein, ...
- Comparative characterization of GPRC5B and GPRC5C LacZ knockin mice; behavioral abnormalities in GPRC5B-deficient mice
[作者:Sano, T; Kim, YJ; Oshima, E; Shimizu, C; Kiyonari, H; Abe, T; Higashi, H; Yamada, K; Hirabayashi, Y,期刊:Biochemical and Biophysical Research Communications, 页码:460-465 , 文章类型: Article,,卷期:2011年412-3]
- Although GPRC5B and GPRC5C are categorized into the G protein-coupled receptor family C, including glutamate receptors, GABA receptors, and taste receptors, their physiological functions remain unknown. Since both recept...
- Negative regulation by Ser/Thr phosphorylation of HadAB and HadBC dehydratases from Mycobacterium tuberculosis type II fatty acid synthase system
[作者:Slama, N; Leiba, J; Eynard, N; Daffe, M; Kremer, L; Quemard, A; Molle, V,期刊:Biochemical and Biophysical Research Communications, 页码:401-406 , 文章类型: Article,,卷期:2011年412-3]
- The type II fatty acid synthase system of mycobacteria is involved in the biosynthesis of major and essential lipids, mycolic acids, key-factors of Mycobacterium tuberculosis pathogenicity. One reason of the remarkable s...
- Genome-wide evaluation and discovery of vertebrate A-to-I RNA editing sites
[作者:Maas, S; Sie, CPG; Stoev, I; Dupuis, DE; Latona, J; Porman, AM; Evans, B; Rekawek, P; Kluempers, V; Mutter, M; Gommans, WM; Lopresti, D,期刊:Biochemical and Biophysical Research Communications, 页码:407-412 , 文章类型: Article,,卷期:2011年412-3]
- RNA editing by adenosine deamination, catalyzed by adenosine deaminases acting on RNA (ADAR), is a post-transcriptional modification that contributes to transcriptome and proteome diversity and is widespread in mammals. ...
- Impedance measurement: A new method to detect ligand-biased receptor signaling
[作者:Kammermann, M; Denelavas, A; Imbach, A; Grether, U; Dehmlow, H; Apfel, CM; Hertel, C,期刊:Biochemical and Biophysical Research Communications, 页码:419-424 , 文章类型: Article,,卷期:2011年412-3]
- Ligand-biased receptor signaling has been proposed for several G-protein coupled receptors including the niacin receptor GPR109A. Coupling to the G(i/o) pathway has been shown to be responsible for the well described tri...
- Crystal structure of the mismatch-specific thymine glycosylase domain of human methyl-CpG-binding protein MBD4
[作者:Zhang, W; Liu, ZL; Crombet, L; Amaya, MF; Liu, YL; Zhang, XR; Kuang, WH; Ma, PT; Niu, LP; Qi, C,期刊:Biochemical and Biophysical Research Communications, 页码:425-428 , 文章类型: Article,,卷期:2011年412-3]
- Methyl-CpG (mCpG) binding domain protein 4 (MBD4) is a member of mammalian DNA glycosylase superfamily. It contains an amino-proximal methyl-CpG binding domain (MBD) and a C-terminal mismatch-specific glycosylase domain,...
- The SARS-CoV heptad repeat 2 exhibits pH-induced helix formation
[作者:Celigoy, J; McReynolds, S; Caffrey, M,期刊:Biochemical and Biophysical Research Communications, 页码:483-486 , 文章类型: Article,,卷期:2011年412-3]
- The heptad repeats 1 and 2 of SARS-CoV spike, termed HR1 and HR2, play critical roles in viral entry. Moreover, HR1 and HR2 derived free peptides are inhibitors of SARS-CoV entry. In this work we used circular dichroism ...
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