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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共22条记录   Escherichia coil SlyD, More Than a Ni(II) Reservoir [作者：Kaluarachchi, H; Zhang, JW; Zamble, DB,期刊：Biochemistry, 页码：10761-10763 , 文章类型： Article，,卷期：2011年50-50] SlyD interacts with HypB and contributes to nickel insertion during [NiFe]-hydrogenase biogenesis. Herein, we provide evidence of SlyD acting as a nickel storage determinant in Escherichia coli and show that this Ni(II) ... Full-Length Human Glutaminase in Complex with an Allosteric Inhibitor [作者：DeLaBarre, B; Gross, S; Fang, C; Gao, Y; Jha, A; Jiang, F; Song, JJ; Wei, WT; Hurov, JB,期刊：Biochemistry, 页码：10764-10770 , 文章类型： Article，,卷期：2011年50-50] Glutaminase (GLS1/2) catalyzes the conversion of L-glutamine to L-glutamate and ammonia. The level of a splice variant of GLS1 (GAC) is elevated in certain cancers, and GAC is specifically inhibited by bis-2-(5-phenylace... Heme Ligand Identification and Redox Properties of the Cytochrome c Synthetase, CcmF [作者：Francisco, BS; Bretsnyder, EC; Rodgers, KR; Kranz, RG,期刊：Biochemistry, 页码：10974-10985 , 文章类型： Article，,卷期：2011年50-50] Cytochrome c maturation in many bacteria, archaea, and plant mitochondria involves the integral membrane protein CcmF, which is thought to function as a cytochrome c synthetase by facilitating the final covalent attachme... Osteogenesis Imperfecta Missense Mutations in Collagen: Structural Consequences of a Glycine to Alanine Replacement at a Highly Charged Site [作者：Xiao, JX; Cheng, HM; Silva, T; Baum, J; Brodsky, B,期刊：Biochemistry, 页码：10771-10780 , 文章类型： Article，,卷期：2011年50-50] Glycine is required as every third residue in the collagen triple helix, and a missense mutation leading to the replacement of even one Gly in the repeating (Gly-Xaa-Yaa)(n) sequence with a larger residue leads to a path... Contribution of Individual Histidines to Prion Protein Copper Binding [作者：Davies, P; McHugh, PC; Hammond, VJ; Marken, F; Brown, DR,期刊：Biochemistry, 页码：10781-10791 , 文章类型： Article，,卷期：2011年50-50] The prion protein is well-established as a copper binding protein. The N-terminus of the protein contains an octameric repeat region with each of the four repeats containing a histidine. The N-terminus has two additional... Identification of Mitochondrial Electron Transport Chain-Mediated NADH Radical Formation by EPR Spin-Trapping Techniques [作者：Matsuzaki, S; Kotake, Y; Humphries, KM,期刊：Biochemistry, 页码：10792-10803 , 文章类型： Article，,卷期：2011年50-50] The mitochondrial electron transport chain (ETC) is a major source of free radical production. However, due to the highly reactive nature of radical species and their short lifetimes, accurate detection and identificatio... The Structural Basis for Homotropic and Heterotropic Cooperativity of Midazolam Metabolism by Human Cytochrome P450 3A4 [作者：Roberts, AG; Yang, J; Halpert, JR; Nelson, SD; Thummel, KT; Atkins, WM,期刊：Biochemistry, 页码：10804-10818 , 文章类型： Article，,卷期：2011年50-50] Human cytochrome P450 3A4 (CYP3A4) metabolizes a significant portion of clinically relevant drugs and often exhibits complex steady-state kinetics that can involve homotropic and heterotropic cooperativity between bound ... A Copper-Methionine Interaction Controls the pH-Dependent Activation of Peptidylglycine Monooxygenase [作者：Bauman, AT; Broers, BA; Kline, CD; Blackburn, NJ,期刊：Biochemistry, 页码：10819-10828 , 文章类型： Article，,卷期：2011年50-50] The pH dependence of native peptidylglycine monooxygenase (PHM) and its M314H variant has been studied in detail. For wild-type (WT) PHM, the intensity of the Cu-S interaction visible in the Cu(I) extended X-ray absorpti... Hydroxylamine Reduction to Ammonium by Plant and Cyanobacterial Hemoglobins [作者：Sturms, R; DiSpirito, AA; Fulton, DB; Hargrove, MS,期刊：Biochemistry, 页码：10829-10835 , 文章类型： Article，,卷期：2011年50-50] Plants often face hypoxic stress as a result of flooding and waterlogged soils. During these periods, they must continue ATP production and nitrogen metabolism if they are to survive. The normal pathway of reductive nitr... A Trimeric Supercomplex of the Oxygen-Tolerant Membrane-Bound [NiFe]-Hydrogenase from Ralstonia eutropha H16 [作者：Frielingsdorf, S; Schubert, T; Pohlmann, A; Lenz, O; Friedrich, B,期刊：Biochemistry, 页码：10836-10843 , 文章类型： Article，,卷期：2011年50-50] The oxygen-tolerant membrane-bound [NiFe]-hydrogenase (MBH) from Ralstonia eutropha H16 consists of three subunits. The large subunit HoxG carries the [NiFe] active site, and the small subunit HoxK contains three [FeS] c... Suppression of EGFR Autophosphorylation by FKBP12 [作者：Mathea, S; Li, S; Schierhorn, A; Jahreis, G; Schiene-Fischer, C,期刊：Biochemistry, 页码：10844-10850 , 文章类型： Article，,卷期：2011年50-50] FK506 binding proteins (FKBPs) represent a subfamily of peptidyl prolyl cis/trans isomerases that can control receptor-mediated intracellular signaling. The prototypic PPIase FKBP12 functionally interacts with EGFR. FKBP... Reconstitution of KCNE1 into Lipid Bilayers: Comparing the Structural, Dynamic, and Activity Differences in Micelle and Vesicle Environments [作者：Coey, AT; Sahu, ID; Gunasekera, TS; Troxel, KR; Hawn, JM; Swartz, MS; Wickenheiser, MR; Reid, RJ; Welch, RC; Vanoye, CG; Kang, CB; Sanders, CR; Lorigan, GA,期刊：Biochemistry, 页码：10851-10859 , 文章类型： Article，,卷期：2011年50-50] KCNE1 (minK), found in the human heart and cochlea, is a transmembrane protein that modulates the voltage-gated potassium KCNQ1 channel. While KCNE1 has previously been the subject of extensive structural studies in lyso... Differential Roles of Cysteine Residues in the Cellular Trafficking, Dimerization, and Function of the High-Density Lipoprotein Receptor, SR-BI [作者：Hu, J; Zhang, ZH; Shen, WJ; Nomoto, A; Azhar, S,期刊：Biochemistry, 页码：10860-10875 , 文章类型： Article，,卷期：2011年50-50] The scavenger receptor, class B, type I (SR-BI) binds high-density lipoprotein (HDL) and mediates selective delivery of cholesteryl esters (CEs) to the liver and steroidogenic cells of the adrenal glands and gonads. Alth... Secondary Nucleating Sequences Affect Kinetics and Thermodynamics of Tau Aggregation [作者：Moore, CL; Huang, MH; Robbennolt, SA; Voss, KR; Combs, B; Gamblin, TC; Goux, WJ,期刊：Biochemistry, 页码：10876-10886 , 文章类型： Article，,卷期：2011年50-50] Tau protein was scanned for highly amyloidogenic sequences in amphiphilic motifs (X)(n)Z, Z(X)(n)Z (n >= 2), or (XZ)(n) (n >= 2), where X is a hydrophobic residue and Z is a charged or polar residue. N-Acetyl peptides ho... Transmembrane Extension and Oligomerization of the CLIC1 Chloride Intracellular Channel Protein upon Membrane Interaction [作者：Goodchild, SC; Angstmann, CN; Breit, SN; Curmi, PMG; Brown, LJ,期刊：Biochemistry, 页码：10887-10897 , 文章类型： Article，,卷期：2011年50-50] Chloride intracellular channel proteins (CLICs) differ from most ion channels as they can exist in both soluble and integral membrane forms. The CLICs are expressed as soluble proteins but can reversibly autoinsert into ... Effect of Cholesterol on the Membrane Interaction of Modelin-5 Isoforms [作者：Dennison, SR; Phoenix, DA,期刊：Biochemistry, 页码：10898-10909 , 文章类型： Article，,卷期：2011年50-50] Modelin-5 isoforms were used to gain an insight into the effects of amidation on antimicrobial selectivity. When tested against Escherichia coli, amidation increased toxicity 10-fold (MIC = 31.25 mu M) while showing limi...