A high performance liquid chromatographic method utilizing an immobilized artificial membrane (IAM HPLC) column has been developed to separate the members of a library containing 38 aurone and thioaurone type structur...
Serum deproteinization is often used as a rapid method for analysis of drugs and small molecules in serum in HPLC. When the recovery of these compounds is calculated based on peak height of aqueous standards treated a...
A precise and accurate flow injection analysis method for the quantification of ticlopidine in pharmaceuticals is described. An aqueous carrier stream, which was entirely prepared with water was chosen for the flow in...
It is shown that very pure sodium hyaluronate (HA) contains small amounts of strongly scattering impurities not detectable on mass scale by refractometric detection, but clearly detectable using low angle light scatte...
In the present study, a novel method was proposed to pack long glass fibers into a narrow-bore capillary for capillary electrochromatography (CEC) applications. The factors that influence the packing process were stud...
The flow-induced degradation of ultra-high molar mass (M) polymers during their passage through a size-exclusion chromatography (SEC) column has been a subject of interest for several decades. Studies in this regard h...
The study of factors influencing the quality of polarimetric signals from chromatographic analysis of mixtures of enantiomers shows that changes in refraction index of mobile phase, analyte concentration, and flow rat...
Results on the chiral separation of ketamine enantiomers by simulated moving bed (SMB) chromatography using microcrystalline cellulose triacetate (MCTA) columns are reported. Experimental data obtained with the SMB la...
Benzo[a]pyrene, after metabolic activation, is known as one of the most potent polycyclic aromatic hydrocarbons that cause a carcinogenic effect. When benzo[a]pyrene is activated by one-electron oxidation to its radic...
Phospholipids are known to cause matrix ionization effects during LC/MS/MS analysis of biological samples. Matrix effects involving endogenous phospholipids in the negative ESI mode have been investigated in this work...
A new procedure for the determination of novel discovery drug substance purity was developed using LC-MS coupled with charged aerosol detection (CAD) in a walk up open access system and chromatographic purity service....