- Cardiac Fibroblast The Renaissance Cell
[作者:Souders, CA; Bowers, SLK; Baudino, TA,期刊:Circulation Research, 页码:1164-1176 , 文章类型: Review,,卷期:2009年105-12]
- The permanent cellular constituents of the heart include cardiac fibroblasts, myocytes, endothelial cells, and vascular smooth muscle cells. Previous studies have demonstrated that there are undulating changes in cardiac...
- Identification of a Novel 14-3-3 zeta Binding Site Within the Cytoplasmic Domain of Platelet Glycoprotein Ib alpha That Plays a Key Role in Regulating the von Willebrand Factor Binding Function of Glycoprotein Ib-IX
[作者:Yuan, YH; Zhang, WL; Yan, R; Liao, Y; Zhao, LL; Ruan, CG; Du, XP; Dai, KS,期刊:Circulation Research, 页码:1177-1185 , 文章类型: Article,,卷期:2009年105-12]
- Rationale: The interaction between platelet glycoprotein (GP) Ib-IX and von Willebrand factor (VWF) is initiated by conformational changes in immobilized VWF and is also regulated by the intraplatelet proteins 14-3-3 zet...
- Extracellular Heat Shock Protein 60, Cardiac Myocytes, and Apoptosis
[作者:Kim, SC; Stice, JP; Chen, L; Jung, JS; Gupta, S; Wang, Y; Baumgarten, G; Trial, J; Knowlton, AA,期刊:Circulation Research, 页码:1186-1186 , 文章类型: Article,,卷期:2009年105-12]
- Rationale: Previously, we have found that changes in the location of intracellular heat shock protein (HSP) 60 are associated with apoptosis. HSP60 has been reported to be a ligand of Toll-like receptor (TLR)-4. Objectiv...
- Angiotensin II-Induced Oxidative Stress Resets the Ca2+ Dependence of Ca2+-Calmodulin Protein Kinase II and Promotes a Death Pathway Conserved Across Different Species
[作者:Palomeque, J; Rueda, OV; Sapia, L; Valverde, CA; Salas, M; Petroff, MV; Mattiazzi, A,期刊:Circulation Research, 页码:1204-1204 , 文章类型: Article,,卷期:2009年105-12]
- Rationale: Angiotensin (Ang) II-induced apoptosis was reported to be mediated by different signaling molecules. Whether these molecules are either interconnected in a single pathway or constitute different and alternativ...
- Changes in Connexin Expression and the Atrial Fibrillation Substrate in Congestive Heart Failure
[作者:Burstein, B; Comtois, P; Michael, G; Nishida, K; Villeneuve, L; Yeh, YH; Nattel, S,期刊:Circulation Research, 页码:1213-1213 , 文章类型: Article,,卷期:2009年105-12]
- Rationale: Although connexin changes are important for the ventricular arrhythmic substrate in congestive heart failure (CHF), connexin alterations during CHF-related atrial arrhythmogenic remodeling have received limite...
- Blockade of Hsp20 Phosphorylation Exacerbates Cardiac Ischemia/Reperfusion Injury by Suppressed Autophagy and Increased Cell Death
[作者:Qian, J; Ren, XP; Wang, XH; Zhang, PY; Jones, WK; Molkentin, JD; Fan, GC; Kranias, EG,期刊:Circulation Research, 页码:1223-1223 , 文章类型: Article,,卷期:2009年105-12]
- Rationale: The levels of a small heat shock protein (Hsp)20 and its phosphorylation are increased on ischemic insults, and overexpression of Hsp20 protects the heart against ischemia/reperfusion injury. However, the mech...
- Left Ventricular and Myocardial Function in Mice Expressing Constitutively Pseudophosphorylated Cardiac Troponin I
[作者:Kirk, JA; MacGowan, GA; Evans, C; Smith, SH; Warren, CM; Mamidi, R; Chandra, M; Stewart, AFR; Solaro, RJ; Shroff, SG,期刊:Circulation Research, 页码:1232-1232 , 文章类型: Article,,卷期:2009年105-12]
- Rationale: Protein kinase (PK)C-induced phosphorylation of cardiac troponin (cTn)I has been shown to regulate cardiac contraction. Objective: Characterize functional effects of increased PKC-induced cTnI phosphorylation ...
- Differentiation of Cardiac Progenitor Cells Into Myocytes Is Regulated by miR-499
[作者:Hosoda, T; Zheng, HQ; Ide-Iwata, N; D'Amario, D; Urbanek, K; Rota, M; Kajstura, J; Anversa, P; Leri, A,期刊:Circulation Research, 页码:5285-5285 , 文章类型: Meeting Abstract,,卷期:2009年105-12]
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- Inpp5f Is a Polyphosphoinositide Phosphatase That Regulates Cardiac Hypertrophic Responsiveness
[作者:Zhu, WT; Trivedi, CM; Zhou, D; Yuan, LJ; Lu, MM; Epstein, JA,期刊:Circulation Research, 页码:1240-1240 , 文章类型: Article,,卷期:2009年105-12]
- Rationale: Cardiac hypertrophy occurs in response to a variety of extrinsic and intrinsic stimuli that impose increased biomechanical stress. The phosphatidylinositol 3-kinase (PI3K)/Akt pathway has previously been stron...
- Shift to an Involvement of Phosphatidylinositol 3-Kinase in Angiotensin II Actions on Nucleus Tractus Solitarii Neurons of the Spontaneously Hypertensive Rat
[作者:Sun, CW; Zubcevic, J; Polson, JW; Potts, JT; Diez-Freire, C; Zhang, Q; Paton, JFR; Raizada, MK,期刊:Circulation Research, 页码:1248-1248 , 文章类型: Article,,卷期:2009年105-12]
- Rationale: Central angiotensin (Ang) II inhibits baroreflex and plays an important role in the pathogenesis of hypertension. However, the underlying molecular mechanisms are still not fully understood. Objective: Our obj...
- Deletion of GSK-3 alpha, but Not GSK-3 beta, Defines an Essential Role in beta-Adrenergic Responsiveness and Identifies a Novel Strategy for beta-Blockade
[作者:Zhou, JB; Woulfe, K; Chen, XW; Gao, EH; Fan, Q; Li, YX; Lal, H; Farber, JL; Shang, XY; Doble, BW; MacAulay, K; Woodgett, JR; Force, TL,期刊:Circulation Research, 页码:5286-5286 , 文章类型: Meeting Abstract,,卷期:2009年105-12]
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- DSAGE Identifies the Orphan Nuclear Receptor, Nur77, as a Downstream Effector of Integrin-Linked Kinase (ILK) in Cardiac-Specific ILK Knockout Mice
[作者:Dai, J; Matsui, T; Abel, ED; Seidman, CE; Seidman, JG; Rosenzweig, A,期刊:Circulation Research, 页码:5287-5287 , 文章类型: Meeting Abstract,,卷期:2009年105-12]
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