- Stereoselective 6-exo Radical Cyclization Using cis-Vinyl Sulfoxide: Practical Total Synthesis of CTX3C
[作者:Yamashita, S; Ishihara, Y; Morita, H; Uchiyama, J; Takeuchi, K; Inoue, M; Hirama, M,期刊:Journal of natural products, 页码:357-364 , 文章类型: Article,,卷期:2011年74-3]
- Ciguatoxins, the principal causative toxins of ciguatera seafood poisoning, are large ladder-like polycyclic ethers. We report a highly stereoselective 6-exo radical cyclization/ring-closing olefin metathesis sequence to...
- Diversonol and Blennolide Derivatives from the Endophytic Fungus Microdiplodia sp.: Absolute Configuration of Diversonol
[作者:Siddiqui, IN; Zahoor, A; Hussain, H; Ahmed, I; Ahmad, VU; Padula, D; Draeger, S; Schulz, B; Meier, K; Steinert, M; Kurtan, T; Florke, U; Pescitelli, G; Krohn, K,期刊:Journal of natural products, 页码:365-373 , 文章类型: Article,,卷期:2011年74-3]
- Chemical investigation of the fungal strain Microdiplodia sp. isolated from the shrub Lycium intricatum led to the isolation of four new compounds: a hexahydroxanthone (2), a 2,3-dihydrochroman-4-one (3), a 7-oxoxanthone...
- Inhibitors of the Oncogenic Transcription Factor AP-1 from Podocarpus latifolius
[作者:Devkota, KP; Ratnayake, R; Colburn, NH; Wilson, JA; Henrich, CJ; McMahon, JB; Beutler, JA,期刊:Journal of natural products, 页码:374-377 , 文章类型: Article,,卷期:2011年74-3]
- An activator protein-1 (AP-1) based bioassay-guided phytochemical investigation on Podocarpus latifolius led to the isolation, of three new sempervirol-type diterpenes, cycloinumakiol (1), inumakal (2), and inumakoic aci...
- Bunodosine 391: An Analgesic Acylamino Acid from the Venom of the Sea Anemone Bunodosoma cangicum
[作者:Zaharenko, AJ; Picolo, G; Ferreira, WA; Murakami, T; Kazuma, K; Hashimoto, M; Cury, Y; de Freitas, JC; Satake, M; Konno, K,期刊:Journal of natural products, 页码:378-382 , 文章类型: Article,,卷期:2011年74-3]
- A new acylamino acid, bunodosine 391 (BDS 391), was isolated from the venom of the sea anemone Bunodosoma cangicum. The structure was elucidated by spectroscopic analyses (2D NMR, ESIMS/MS) and verified by its synthesis....
- Phomalevones A-C: Dimeric and Pseudodimeric Polyketides from a Fungicolous Hawaiian Isolate of Phoma sp. (Cucurbitariaceae)
[作者:Shim, SH; Baltrusaitis, J; Gloer, JB; Wicklow, DT,期刊:Journal of natural products, 页码:395-401 , 文章类型: Article,,卷期:2011年74-3]
- Phomalevones A-C (1-3), three new compounds with bis-dihydroxanthone and bis-benzophenone systems, were isolated from cultures of a Hawaiian isolate of Phoma sp. (MYC-1734 = NRRL, 39060; Cucurbitariaceae). The structures...
- Comprehensive Study of Alkaloids from Crinum asiaticum var. sinicum Assisted by HPLC-DAD-SPE-NMR
[作者:Chen, CK; Lin, FH; Tseng, LH; Jiang, CL; Lee, SS,期刊:Journal of natural products, 页码:411-419 , 文章类型: Article,,卷期:2011年74-3]
- A comprehensive study of the alkaloids present in the leaves of Crinum asiaticum var. sinicum, assisted by HPLC-SPE-NMR, led to the characterization of 21 compounds of similar polarity on an analytical scale. Thirteen of...
- Improvement of the Enediyne Antitumor Antibiotic C-1027 Production by Manipulating Its Biosynthetic Pathway Regulation in Streptomyces globisporus
[作者:Chen, YH; Yin, M; Horsman, GP; Shen, B,期刊:Journal of natural products, 页码:420-424 , 文章类型: Article,,卷期:2011年74-3]
- The production of C-1027 in Streptomyces globisporus was previously increased 2- to 3-fold by manipulating three pathway-specific activators, SgcR1, SgcR2, and SgcR3. In this study, we have further characterized two puta...
- Stereochemical Investigations of Isochromenones and Isobenzofuranones Isolated from Leptosphaeria sp. KTC 727
[作者:Tayone, WC; Honma, M; Kanamaru, S; Noguchi, S; Tanaka, K; Nehira, T; Hashimoto, M,期刊:Journal of natural products, 页码:425-429 , 文章类型: Article,,卷期:2011年74-3]
- Two new metabolites, (R)-3,4-dihydro-4,6,8-trihydroxy-4,5-dimethyl-3-methyleneisochromen-1-one (1) and (R)-7-hydroxy-3,4(S)-1-hydroxyethyl)-5-methoxy-3,4-dimethylisobenzofuran-1(3H)-one (2), were isolated along with two ...
- Xestoproxamines A-C from Neopetrosia proxima. Assignment of Absolute Stereostructure of Bis-piperidine Alkaloids by Integrated Degradation-CD Analysis
[作者:Morinaka, BI; Molinski, TF,期刊:Journal of natural products, 页码:430-440 , 文章类型: Article,,卷期:2011年74-3]
- The complete stereostructures of xestoproxamines A-C, from the Bahamian sponge Neopetrosia proxima, were assigned from spectroscopic analysis, including MS, 2D NMR, and integrated degradation-CD analysis. Two new CD appl...
- Nonterpenoid C-15 Acetogenins from Laurencia marilzae
[作者:Gutierrez-Cepeda, A; Fernandez, JJ; Gil, LV; Lopez-Rodriguez, M; Norte, M; Souto, ML,期刊:Journal of natural products, 页码:441-448 , 文章类型: Article,,卷期:2011年74-3]
- Eight new halogenated C-15 acetogenins, 1-8, were isolated from the organic extract of the red alga Laurencia marilzae. The structure elucidation and the assignments of the relative configurations were established by ext...
- Two Brominated Cyclic Dipeptides Released by the Coldwater Marine Sponge Geodia barretti Act in Synergy As Chemical Defense
[作者:Sjogren, M; Jonsson, PR; Dahstrom, M; Lundalv, T; Burman, R; Goransson, U; Bohlin, L,期刊:Journal of natural products, 页码:449-454 , 文章类型: Article,,卷期:2011年74-3]
- The current work shows that two structurally similar cyclodipeptides, barettin (1) and 8,9-dihydrobarettin (2), produced by the coldwater marine sponge Geodia barretti Bowerbank act in synergy to deter larvae of surface ...
- Epiafzelechin from the Root Bark of Cassia sieberiana: Detection by DART Mass Spectrometry, Spectroscopic Characterization, and Antioxidant Properties
[作者:Kpegba, K; Agbonon, A; Petrovic, AG; Amouzou, E; Gbeassor, M; Proni, G; Nesnas, N,期刊:Journal of natural products, 页码:455-459 , 文章类型: Article,,卷期:2011年74-3]
- The root bark of Cassia sieberiana was analyzed using direct analysis in real time mass spectrometry, and a main flavonoid component with an [M + H](+) mass of 275 was identified. The flavonoid, epiafzelechin, was isolat...
- Absolute Configuration of (-)-Gambogic Acid, an Antitumor Agent
[作者:Ren, YL; Yuan, CH; Chai, HB; Ding, YQ; Li, XC; Ferreira, D; Kinghorn, AD,期刊:Journal of natural products, 页码:460-463 , 文章类型: Article,,卷期:2011年74-3]
- (-)-Gambogic acid (1), a biologically active "caged xanthone" from gamboge, the dried resin of Garcinia hanburyi, is of interest as a potential anticancer agent. The planar structure of (-)-gambogic acid has been determi...
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