- The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways
[作者：Alessio, N; Squillaro, T; Cipollaro, M; Bagella, L; Giordano, A; Galderisi, U,期刊：Oncogene, 页码：5452-5463 , 文章类型： Article，,卷期：2010年29-40]
- We focused our attention on brahma-related gene 1 (BRG1), the ATPase subunit of the SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeling complex, and analyzed its role in mesenchymal stem cell (MSC) biology. We h...
- PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21
[作者：Hu, F; Gartenhaus, RB; Eichberg, D; Liu, Z; Fang, HB; Rapoport, AP,期刊：Oncogene, 页码：5464-5474 , 文章类型： Article，,卷期：2010年29-40]
- PBK/TOPK (PDZ-binding kinase, T-LAK-cell-originated protein kinase) is a serine-threonine kinase that is overexpressed in a variety of tumor cells but its role in oncogenesis remains unclear. Here we show, by co-immunopr...
- Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion
[作者：Lau, KM; Chan, QKY; Pang, JCS; Li, KKW; Yeung, WW; Chung, NYF; Lui, PC; Tam, YS; Li, HM; Zhou, L; Wang, Y; Mao, Y; Ng, HK,期刊：Oncogene, 页码：5475-5489 , 文章类型： Article，,卷期：2010年29-40]
- Minichromosome maintenance (MCM) proteins 2-7 are important in DNA replication licensing. Functional roles beyond licensing are speculated. In addition, significances in medulloblastoma (MB) remain unclear. In this study...
- PIM1 kinase is destabilized by ribosomal stress causing inhibition of cell cycle progression
[作者：Iadevaia, V; Caldarola, S; Biondini, L; Gismondi, A; Karlsson, S; Dianzani, I; Loreni, F,期刊：Oncogene, 页码：5490-5499 , 文章类型： Article，,卷期：2010年29-40]
- PIM1 is a constitutively active serine/threonine kinase regulated by cytokines, growth factors and hormones. It has been implicated in the control of cell cycle progression and apoptosis and its overexpression has been a...
- ZNF217, a candidate breast cancer oncogene amplified at 20q13, regulates expression of the ErbB3 receptor tyrosine kinase in breast cancer cells
[作者：Krig, SR; Miller, JK; Frietze, S; Beckett, LA; Neve, RM; Farnham, PJ; Yaswen, PI; Sweeney, CA,期刊：Oncogene, 页码：5500-5510 , 文章类型： Article，,卷期：2010年29-40]
- Understanding the mechanisms underlying ErbB3 overexpression in breast cancer will facilitate the rational design of therapies to disrupt ErbB2-ErbB3 oncogenic function. Although ErbB3 overexpression is frequently observ...
- SUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PML
[作者：Wimmer, P; Schreiner, S; Everett, RD; Sirma, H; Groitl, P; Dobner, T,期刊：Oncogene, 页码：5511-5522 , 文章类型： Article，,卷期：2010年29-40]
- The E1B-55K product from human adenovirus is a substrate of the small ubiquitin-related modifier (SUMO)-conjugation system. SUMOylation of E1B-55K is required to transform primary mammalian cells in cooperation with aden...
- The inhibition of Bid expression by Akt leads to resistance to TRAIL-induced apoptosis in ovarian cancer cells
[作者：Goncharenko-Khaider, N; Lane, D; Matte, I; Rancourt, C; Piche, A,期刊：Oncogene, 页码：5523-5536 , 文章类型： Article，,卷期：2010年29-40]
- Epithelial ovarian cancer (EOC) cells often show increased activity of the PI3K/Akt pathway. In addition, we have previously shown that EOC ascites induce Akt activation in the tumor necrosis factor-related apoptosis-ind...
- MCPH1/BRIT1 limits ionizing radiation-induced centrosome amplification
[作者：Brown, JAL; Bourke, E; Liptrot, C; Dockery, P; Morrison, CG,期刊：Oncogene, 页码：5537-5544 , 文章类型： Article，,卷期：2010年29-40]
- Microcephalin (MCPH1/BRIT1) is a potential tumour suppressor that localizes to the centrosome, forms ionizing radiation-induced nuclear foci (IRIF) and is involved in the DNA damage checkpoints that ensure genome stabili...
- MOS, aneuploidy and the ploidy cycle of cancer cells
[作者：Erenpreisa, J; Cragg, MS,期刊：Oncogene, 页码：5447-5451 , 文章类型： Review，,卷期：2010年29-40]
- After DNA or spindle damage, p53-defective tumor cells undergo a complex cycle of reversible polyploidy. How this process occurs and more importantly, why, has recently become the focus of several research groups, prompt...
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