- Enzymatic Kinetic Resolution of Silybin Diastereoisomers
[作者:Monti, D; Gazak, R; Marhol, P; Biedermann, D; Purchartova, K; Fedrigo, M; Riva, S; Kren, V,期刊:Journal of natural products, 页码:613-619 , 文章类型: Article,,卷期:2010年73-4]
- In nature, the flavonolignan silybin (1) occurs as a mixture of two diastereomers, silybin A and silybin B, which in a number of biological assays exhibit different activities. A library of hydrolases (lipases, esterases...
- Sterols and Terpenoids from Melia azedarach
[作者:Tan, QG; Li, XN; Chen, H; Feng, T; Cai, XH; Luo, XD,期刊:Journal of natural products, 页码:693-697 , 文章类型: Article,,卷期:2010年73-4]
- Three new sterols (1-3) including an unprecedented ring A-seco natural product (1), five new terpenoids (4-8), and 15 known compounds were isolated from the bark of Melia azedarach. Their structures were elucidated by me...
- Antiviral and Anti-inflammatory Metabolites from the Soft Coral Sinularia capillosa
[作者:Cheng, SY; Huang, KJ; Wang, SK; Wen, ZH; Chen, PW; Duh, CY,期刊:Journal of natural products, 页码:771-775 , 文章类型: Article,,卷期:2010年73-4]
- Chemical investigations of the soft coral Sinularia capillosa resulted in the isolation of one new tetraprenylbenzoquinone, capilloquinone (1), two new furanobenzosesquiterpenoids, capillobenzopyranol (2) and capillobenz...
- Arenamides A-C, Cytotoxic NF kappa B Inhibitors from the Marine Actinomycete Salinispora arenicola (vol 72, pg 396, 2009)
[作者:Asolkar, RN; Freel, KC; Jensen, PR; Fenical, W; Kondratyuk, TP; Park, EJ; Pezzuto, JM,期刊:Journal of natural products, 页码:796-796 , 文章类型: Correction,,卷期:2010年73-4]
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- Eremophilane-Type Sesquiterpenes from the Fungus Xylaria sp BCC 21097
[作者:Isaka, M; Chinthanom, P; Boonruangprapa, T; Rungjindamai, N; Pinruan, U,期刊:Journal of natural products, 页码:683-687 , 文章类型: Article,,卷期:2010年73-4]
- Seven new eremophilane-type sesquiterpenoids (1-5, 7, and 8) and the known mairetolide F (6) were isolated from the endophytic Xylaria sp. BCC 21097. A new furofurandione (9) was also isolated from the fungal extract. Th...
- Jacaranone-Derived Glucosidic Esters from Jacaranda glabra and Their Activity against Plasmodium falciparum
[作者:Gachet, MS; Kunert, O; Kaiser, M; Brun, R; Munoz, RA; Bauer, R; Schuhly, W,期刊:Journal of natural products, 页码:553-556 , 文章类型: Article,,卷期:2010年73-4]
- In a survey of plants from Ecuador with antiprotozoal activity, Jacaranda glabra was found to show promising activity against the Plasmodium falciparum K1 strain. Subsequently, activity-guided isolation of the dichlorome...
- JBIR-22, An Inhibitor for Protein-Protein Interaction of the Homodimer of Proteasome Assembly Factor 3
[作者:Izumikawa, M; Hashimoto, J; Hirokawa, T; Sugimoto, S; Kato, T; Takagi, M; Shin-ya, K,期刊:Journal of natural products, 页码:628-631 , 文章类型: Article,,卷期:2010年73-4]
- Proteasome assembling chaperone (PAC) 3 acts as a homodimer and plays an important role in proteasome formation. We screened JBIR-22 (1) as an inhibitor for protein protein interaction (PPI) of PAC3 homodimer from our na...
- Phenolic Constituents of the Aerial Parts of Cimicifuga simplex and Cimicifuga japonica
[作者:Iwanaga, A; Kusano, G; Warashina, T; Miyase, T,期刊:Journal of natural products, 页码:609-612 , 文章类型: Article,,卷期:2010年73-4]
- Chemical investigation of the aerial parts of Cimicifuga simplex afforded four new fukinolic acid analogues, cimicifugic acids K-N (1-4), and 10 known compounds, and C. japonica afforded three new fukinolic acid analogue...
- Structure and Anti-TB Activity of Trachylobanes from the Liverwort Jungermannia exsertifolia ssp. cordifolia
[作者:Scher, JM; Schinkovitz, A; Zapp, J; Wang, YH; Franzblau, SG; Becker, H; Lankin, DC; Pauli, GF,期刊:Journal of natural products, 页码:656-663 , 文章类型: Article,,卷期:2010年73-4]
- In the critical search for new antituberculosis lead compounds, bryophytes represent a largely untapped resource of chemically diverse structures. From the liverwort Jungermannia exsertifolia subsp. cordifolia, 11 new tr...
- Automated High-Throughput System to Fractionate Plant Natural Products for Drug Discovery
[作者:Tu, Y; Jeffries, C; Ruan, H; Nelson, C; Smithson, D; Shelat, AA; Brown, KM; Li, XC; Hester, JP; Smillie, T; Khan, IA; Walker, L; Guy, K; Yan, B,期刊:Journal of natural products, 页码:751-754 , 文章类型: Article,,卷期:2010年73-4]
- The development of an automated, high-throughput fractionation procedure to prepare and analyze natural product libraries for drug discovery screening is described. Natural products obtained from plant materials worldwid...
- Cytoglobosins A-G, Cytochalasans from a Marine-Derived Endophytic Fungus, Chaetomium globosum QEN-14
[作者:Cui, CM; Li, XM; Li, CS; Proksch, P; Wang, BG,期刊:Journal of natural products, 页码:729-733 , 文章类型: Article,,卷期:2010年73-4]
- Cytoglobosins A-G (1-7), seven new cytochalasan derivatives, along with two structurally related known compounds, isochaetoglobosin D (8) and chaetoglobosin F-ex (9), were isolated and identified from the cultures of Cha...
- Cytotoxic Activities of Several Geranyl-Substituted Flavanones
[作者:Smejkal, K; Svacinova, J; Slapetova, T; Schneiderova, K; Dall'Acqua, S; Innocenti, G; Zavalova, V; Kollar, P; Chudik, S; Marek, R; Julinek, O; Urbanova, M; Kartal, M; Csollei, M; Dolezal, K,期刊:Journal of natural products, 页码:568-572 , 文章类型: Article,,卷期:2010年73-4]
- Nine geranylated flavanones isolated from the fruits of Paulownia tomentosa (4-12) and two from the roots of Moms alba (13 and 14) were examined for cytotoxicity to selected human cancer cell lines and normal human fibro...
- Labdane Diterpenes from the Aerial Parts of Curcuma comosa Enhance Fetal Hemoglobin Production in an Erythroid Cell Line
[作者:Chokchaisiri, R; Chaneiam, N; Svasti, S; Fucharoen, S; Vadolas, J; Suksamran, A,期刊:Journal of natural products, 页码:724-728 , 文章类型: Article,,卷期:2010年73-4]
- Three new labdane diterpenes, curcucomosin A-C (1-3), four known labdane diterpenes, 4-7, and a known diarylheptanoid, 8, were isolated from the aerial parts of Curcuma comosa. The structures of the new diterpenes were e...
- Lactonecembranoids from Croton laevigatus
[作者:Zou, GA; Ding, G; Su, ZH; Yang, JS; Zhang, HW; Peng, CZ; Aisa, HA; Zou, ZM,期刊:Journal of natural products, 页码:792-795 , 文章类型: Article,,卷期:2010年73-4]
- Six new cembranoids, laevigatlactones A-F (1-6), and the known compound neocrotocembraneic acid (7) were isolated from leaves of Croton laevigatus. Their structures were elucidated on the basis of spectroscopic analysis,...
- Structure Elucidation at the Nanomole Scale. 3. Phorbasides G-I from Phorbas sp.
[作者:Dalisay, DS; Molinski, TF,期刊:Journal of natural products, 页码:679-682 , 文章类型: Article,,卷期:2010年73-4]
- Three new phorbasides (G-I), chlorocyclopropyl ene-yne macrolide glycosides, were isolated from the sponge Phorbas sp. in yields of 7-9.5 mu g and fully characterized by MS, CD, and microcryoprobe NMR. The structures of ...
- Structure of Minor Carotenoids from the Crown-of-Thorns Starfish, Acanthaster planci
[作者:Maoka, T; Akimoto, N; Terada, Y; Komemushi, S; Harada, R; Sameshima, N; Sakagami, Y,期刊:Journal of natural products, 页码:675-678 , 文章类型: Article,,卷期:2010年73-4]
- Four new carotenoids, named 4-ketodeepoxyneoxanthin (1), 4-keto-4'-hydroxydiatoxanthin (2), 3'-epigobiusxanthin (3), and 7,8-dihydrodiadinoxanthin (4), were isolated from the crown-of-thorns starfish, Acanthaster planci....
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