- Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens
[作者：Carette, JE; Guimaraes, CP; Varadarajan, M; Park, AS; Wuethrich, I; Godarova, A; Kotecki, M; Cochran, BH; Spooner, E; Ploegh, HL; Brummelkamp, TR,期刊：Science, 页码：1231-1235 , 文章类型： Article，,卷期：2009年326-5957]
- Loss-of-function genetic screens in model organisms have elucidated numerous biological processes, but the diploid genome of mammalian cells has precluded large-scale gene disruption. We used insertional mutagenesis to d...
|