- Aptamers for allosteric regulation
[作者:VINKENBORG JAN L; KARNOWSKI NORA; FAMULOK MICHAEL,期刊:NATURE CHEMICAL BIOLOGY, 页码:519-527 , 文章类型: Review,,卷期:2011年7-8]
- Aptamers are useful for allosteric regulation because they are nucleic acid-based structures in which ligand binding induces conformational changes that may alter the function of a connected oligonucleotide at a distant ...
- A screen for regulators of survival of motor neuron protein levels
[作者:MAKHORTOVA NINA R; HAYHURST MONICA; CERQUEIRA ANTONIO; SINORANDERSON AMY D; ZHAO WENNING; HEISER PATRICK W; ARVANITES ANTHONY C; DAVIDOW LANCE S; WALDON ZACHARY O; STEEN JUDITH A; LAM KELVIN; NGO HIEN D; RUBIN LEE L,期刊:NATURE CHEMICAL BIOLOGY, 页码:544-552 , 文章类型: Article,,卷期:2011年7-8]
- The motor neuron disease spinal muscular atrophy (SMA) results from mutations that lead to low levels of the ubiquitously expressed protein survival of motor neuron (SMN). An ever-increasing collection of data suggests t...
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