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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共21条记录   Fluorescence and UV Resonance Raman Study of Peptide-Vesicle Interactions of Human Cathelicidin LL-37 and Its F6W and F17W Mutants [作者：Gable, JE; Schlamadinger, DE; Cogen, AL; Gallo, RL; Kim, JE,期刊：Biochemistry, 页码：11264-11272 , 文章类型： Article，,卷期：2009年48-47] LL-37 is a broad-spectrum human antimicrobial peptide in the cathelicidin family. Potency assays in the form of minimal inhibitory concentration and vesicle leakage indicate that the single-tryptophan mutants, F6W and F1... A FRET-Based Method for Probing the Conformational Behavior of an Intrinsically Disordered Repeat Domain from Bordetella pertussis Adenylate Cyclase [作者：Szilvay, GR; Blenner, MA; Shur, O; Cropek, DM; Banta, S,期刊：Biochemistry, 页码：11273-11282 , 文章类型： Article，,卷期：2009年48-47] A better understanding of the conformational changes exhibited by intrinsically disordered proteins is necessary as we continue to unravel their myriad biological functions. In repeats in toxin (RTX) domains, calcium bin... Structural Basis of the Aberrant Receptor Binding Properties of Hagfish and Lamprey Insulins [作者：Sajid, W; Holst, PA; Kiselyov, VV; Andersen, AS; Conlon, JM; Kristensen, C; Kjeldsen, T; Whittaker, J; Chan, SJ; De Meyts, P,期刊：Biochemistry, 页码：11283-11295 , 文章类型： Article，,卷期：2009年48-47] The insulin from the Atlantic hagfish (Myxine glutinosa) has been one of the most studied insulins from both a structural and a biological viewpoint; however, some aspects of its biology remain controversial, and there h... Mechanism of the Translation Termination Reaction on the Ribosome [作者：Trobro, S; Aqvist, J,期刊：Biochemistry, 页码：11296-11303 , 文章类型： Article，,卷期：2009年48-47] Ribosomal release factors (RFs) catalyze the termination of protein synthesis by triggering hydrolysis of the peptidyl-tRNA ester bond in the peptidyl transferase center of the ribosome. With new medium-resolution crysta... Dynamics and Energetics of the Base Flipping Conformation Studied with Base Pair-Mimic Nucleosides [作者：Nakano, S; Oka, H; Uotani, Y; Uenishi, K; Fujii, M; Sugimoto, N,期刊：Biochemistry, 页码：11304-11311 , 文章类型： Article，,卷期：2009年48-47] A base flipping conformation is found in many biological processes, including DNA repair and DNA and RNA modification processes. To investigate the dynamics and energetics of this unusual conformation in a double helix, ... pH-Dependent Configurations of a 5-Chlorouracil-Guanine Base Pair [作者：Theruvathu, JA; Kim, CH; Darwanto, A; Neidigh, JW; Sowers, LC,期刊：Biochemistry, 页码：11312-11318 , 文章类型： Article，,卷期：2009年48-47] Hypochlorous acid (HOCl) from activated neutrophils at sites of inflammation can react with and damage biological molecules, including nucleic acids. The reaction of HOCl with cytosine analogues can generate multiple pro... Calmodulin Is a Nonessential Activator of Secretory Phospholipase A(2) [作者：Kovacic, L; Novinec, M; Petan, T; Baici, A; Krizaj, I,期刊：Biochemistry, 页码：11319-11328 , 文章类型： Article，,卷期：2009年48-47] Ammodytoxins are presynaptically neurotoxic snake venom group IIA secreted phospholipase A(2) enzymes that interact specifically with calmodulin in the cytosol of nerve cells. We show that calmodulin behaves as an activa... Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale [作者：Peiro-Salvador, T; Ces, O; Templer, RH; Seddon, AM,期刊：Biochemistry, 页码：11149-11151 , 文章类型： Article，,卷期：2009年48-47] The effects of biological buffers on lipids have not been fully Investigated because of the long-standing assumption that these buffers are too hydrophilic to substantially interact with the lipid membrane. We present ev... Reduced Digestive Vacuolar Accumulation of Chloroquine Is Not Linked to Resistance to Chloroquine Toxicity [作者：Cabrera, M; Paguio, MF; Xie, CA; Roepe, PD,期刊：Biochemistry, 页码：11152-11154 , 文章类型： Article，,卷期：2009年48-47] Chloroquine (CQ) accumulation studies in live malaria parasites are typically conducted at low nanomolar CQ concentrations, and definition of CQ resistance (CQR) has been via growth inhibition assays versus low-dose CQ (... Assembly of Hybrid Bacteriophage Q beta Virus-like Particles [作者：Brown, SD; Fiedler, JD; Finn, MG,期刊：Biochemistry, 页码：11155-11157 , 文章类型： Article，,卷期：2009年48-47] Bacteriophage Q beta coat protein forms uniform virus-like particles when expressed recombinantly in a variety of organisms. We have inserted the IgG-binding Z domain at the carboxy terminus of the coat protein and coexp... Interaction of the Disordered Yersinia Effector Protein YopE with Its Cognate Chaperone SycE [作者：Hu, X; Lee, MS; Wallqvist, A,期刊：Biochemistry, 页码：11158-11160 , 文章类型： Article，,卷期：2009年48-47] We describe an efficient approach to model the binding interaction of the disordered effector protein to its cognate chaperone in the type III secretion system (T3SS). Starting from de novo models, we generated ensembles... The Mechanistic Architecture of Thermostable Pyrococcus furiosus Family B DNA Polymerase Motif A and Its Interaction with the dNTP Substrate [作者：Kennedy, EM; Hergott, C; Dewhurst, S; Kim, B,期刊：Biochemistry, 页码：11161-11168 , 文章类型： Article，,卷期：2009年48-47] Thermostable DNA polymerases isolated from archaeal organisms have not been completely characterized kinetically and require further study if we are to understand both their dNTP binding mechanism and their role within t... Duplex Formation at the 5 ' End Affects the Quadruplex Conformation of the Human Telomeric Repeat Overhang in Sodium but Not in Potassium [作者：Gaynutdinov, TI; Brown, P; Neumann, RD; Panyutin, IG,期刊：Biochemistry, 页码：11169-11177 , 文章类型： Article，,卷期：2009年48-47] Human telomeres contain numerous copies of the (TTAGGG)(n).(AATCCC)(n) repeated sequence With multiple TTAGGG repeats in 3' single-stranded overhangs. Single-stranded oligonucleotides consisting of four TTAGGG repeats ca... Kinetics of Stop Codon Recognition by Release Factor 1 [作者：Hetrick, B; Lee, K; Joseph, S,期刊：Biochemistry, 页码：11178-11184 , 文章类型： Article，,卷期：2009年48-47] Recognition of stop codons by class 1 release factors is a fundamental step in the termination phase of protein synthesis. Since premature termination is costly to the cell, release factors have to efficiently discrimina... Interaction of the Tim44 C-Terminal Domain with Negatively Charged Phospholipids [作者：Marom, M; Safonov, R; Amram, S; Avneon, Y; Nachliel, E; Gutman, M; Zohary, K; Azem, A; Tsfadia, Y,期刊：Biochemistry, 页码：11185-11195 , 文章类型： Article，,卷期：2009年48-47] The translocation of proteins from the cytosol into the mitochondrial matrix is mediated by the coordinated action of the TOM complex in the Outer membrane, as well as the TIM23 complex and its associated protein import ... Dynamics of Activation of Lecithin: Cholesterol Acyltransferase by Apolipoprotein A-I [作者：Jones, MK; Catte, A; Li, L; Segrest, JP,期刊：Biochemistry, 页码：11196-11210 , 文章类型： Article，,卷期：2009年48-47] The product of transesterification of phospholipid acyl chains and unesterified cholesterol (UC) by the enzyme lecithin:cholesterol acyltransferase (LCAT) is cholesteryl ester (CE). Activation of LCAT by apolipoprotein (...