Not only the self-aggregation of dendritic polycarboxylates into structurally persistent micelles, but also that of the micelles themselves into superlattices is controlled by alkali-metal counterions and shows a pronoun...
The development and application of chiral, non-racemic Re-v-oxo complexes to the enantioselective reduction of prochiral ketones is described. In addition to the enantioselective reduction of prochiral ketones, we report...
Our knowledge of the biological relevance of regions of chemical space is shaped, in large part, by the synthetic accessibility of small molecules. Historically, however, chemists have explored chemical space in an excep...
A detailed study on the solid-phase synthesis of lipidated peptides of the Ras family employing the Ellman sulfonamide linker is reported. Using the C-terminal N-Ras sequence, critical issues such as lipidated amino acid...
Compounds [Cp*2M2O5] (M=Mo, 1; W, 2) are efficient pre-catalysts for cyclooctene (COE) epoxidation by aqueous H2O2 in acetonitrile/toluene. The reaction is quantitative, selective and takes place approximately 50 times f...
Novel donor- and/or acceptor-substituted cross-conjugated carbocycles based on quinoids or expanded quinoids, with radiaannulene perimeters, were prepared and investigated to validate proaromaticity as a concept for redu...
A straightforward two-step synthesis of trans-3,4-disubstituted succinimides through a palladium-catalyzed Sonogashira reaction and an iron-catalyzed double carbonylation is described. In situ oxidative dehydrogenation g...
Platencin is a novel antibiotic which is active against multiresistant pathogens. We describe efficient syntheses of three platencin analogues of varying activities which allow further conclusions about the pharmacophori...
Oxidative halogenation with trityl chloride provides convenient access to Ce-IV and U-IV chloroamides [M(N{SiMe3}(2))(3)Cl] and their N-heterocyclic carbene derivatives, [M(L)(N-{SiMe3}(2))(2)Cl] (L= OCMe2CH2(CNCH2-CH(2)...
Antimicrobial activity of trimethoprim/sulfamethoxazole (SXT) against Staphylococcus aureus (S. aureus) is antagonized by thymidine, which is abundant in infected or inflamed human tissue. To restore the antimicrobial ac...
Several new fullerene heptamethine conjugates, which absorb as far as into the infrared spectrum as 800 nm, have been synthesized and fully characterized by physicochemical means. In terms of optical and electrochemical ...
The efficient green phosphor Ba3Si6O12N2:Eu2+ and its solid-solution series Ba3-xSrxSi6O12N2 (with x approximate to 0.4 and 1) were synthesized in a radio-frequency furnace under nitrogen atmosphere at temperatures up to...
The enantioselective allylic alkylation of (E)-1,3-diphenylallyl acetate was studied to clarify the heterogeneous or homogeneous character of the Pd/Al2O3-(R)-BINAP catalyst system. A combined approach was applied: the c...
Although O-2 activation by metals such as iron and copper has been a matter of intensive research in the last decades, this type of chemistry for nickel systems is still in its infancy. Moreover, studies regarding the ox...
The easily installed and removed N-(2-pyridyl)sulfonyl group exerts complete C2 regiocontrol over the Pd-II-catalysed C-H alkenylation of indoles and pyrroles, affording the corresponding products in good isolated yields...