- State-of-the-Art Therapeutic Medical Countermeasures for Bacterial Threat Agents
[作者:Stundick, MV; Metz, M; Sampath, A; Larsen, JC,期刊:Drug Development Research, 页码:361-378 , 文章类型: Article,,卷期:2011年72-5]
- In the event of another bioterrorism attack with a bacterial agent, antibiotics will be critical medical countermeasures to have in the US Strategic National Stockpile. Conventional antibiotics such as ciprofloxacin, dox...
- Improved In Vitro Dissolution Parameters and In Vivo Hypolipidemic Efficiency of Atorvastatin Calcium Through the Formation of Hydrophilic Inclusion Complex With Cyclodextrins
[作者:Hussein, AK; Ibrahim, MA; Amin, MA; Ahmed, OAA; Afouna, MI,期刊:Drug Development Research, 页码:379-390 , 文章类型: Article,,卷期:2011年72-5]
- An aim of the present study was to improve the dissolution of the inherently low water solubility hypolipidemic agent, Atorvastatin calcium (ATC), through the preparation and characterization of ATC with cyclodextrins (C...
- Evaluation of the Interaction Between Tramadol and Diclofenac in Several Models of Nociception in the Rat
[作者:Rodriguez-Silverio, J; Deciga-Campos, M; Reyes-Garcia, G; Carrasco-Portugal, MD; Flores-Murrieta, FJ,期刊:Drug Development Research, 页码:391-396 , 文章类型: Article,,卷期:2011年72-5]
- Diclofenac and tramadol are drugs widely used for the treatment of pain. However, side effects may limit their use. As both drugs produce side effects that are dose-dependent, it seems appropriate to combine them in orde...
- Synergistic Interaction of Diclofenac, Benfotiamine, and Resveratrol in Experimental Acute Pain
[作者:Montiel-Ruiz, RM; Granados-Soto, V; Garcia-Jimenez, S; Reyes-Garcia, G; Flores-Murrieta, FJ; Deciga-Campos, M,期刊:Drug Development Research, 页码:397-404 , 文章类型: Article,,卷期:2011年72-5]
- This study was designed to evaluate the possible synergistic antinociceptive interactions between diclofenac, benfotiamine, and resveratrol on acetic acid-induced nociception in mice. Isobolographic analyses were used to...
- Design and Synthesis of Novel NO-Donor-Ferulic Acid Hybrids as Potential Antiatherosclerotic Drug Candidates
[作者:Li, NG; Wang, R; Shi, ZH; Tang, YP; Li, BQ; Wang, ZJ; Song, SL; Qian, LH; Li, W; Yang, JP; Yao, LJ; Xi, JZ; Xu, J; Feng, F; Qian, DW; Duan, JA,期刊:Drug Development Research, 页码:405-415 , 文章类型: Article,,卷期:2011年72-5]
- Novel NO-donor-ferulic acid hybrids were designed and synthesized through a symbiotic approach using ferulic acid and three different NO-donating groups, such as nitric ester, 4-hydroxyl-3-phenylfuroxan, and 4-hydroxymet...
- Evaluation of the pK(a) Values and Ionization Sequence of Bumetanide Using (1)H and (13)C NMR and UV Spectroscopy
[作者:Song, BB; Galande, AK; Kodukula, K; Moos, WH; Miller, SM,期刊:Drug Development Research, 页码:416-426 , 文章类型: Article,,卷期:2011年72-5]
- Non-thiazide loop diuretics such as bumetanide and furosemide are well-established medicaments, with varying substituents that alter their chemical properties in ways that affect biological parameters, including biodistr...
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