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Improved In Vitro Dissolution Parameters and In Vivo Hypolipidemic Efficiency of Atorvastatin Calcium Through the Formation of Hydrophilic Inclusion Complex With Cyclodextrins

  作者 Hussein, AK; Ibrahim, MA; Amin, MA; Ahmed, OAA; Afouna, MI  
  选自 期刊  Drug Development Research;  卷期  2011年72-5;  页码  379-390  
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[摘要]An aim of the present study was to improve the dissolution of the inherently low water solubility hypolipidemic agent, Atorvastatin calcium (ATC), through the preparation and characterization of ATC with cyclodextrins (CDs) inclusion complexes employing d

 
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