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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   CANAGLIFLOZIN Sodium/Glucose Cotransporter 2 Inhibitor Treatment of Type 2 Diabetes Treatment of Obesity [作者：Chao, EC,期刊：Drugs of the Future, 页码：351-357 , 文章类型： Article，,卷期：2011年36-5] Sodium/glucose cotransporters (SGLTs) serve a critical role in the reclamation of glucose in the kidney. Blocking this reabsorption, and thus increasing the amount of glucose excretion, has been proposed as a novel strat... LIXIVAPTAN Vasopressin V(2) Receptor Antagonist Treatment of Heart Failure Treatment of Hyponatremia [作者：Daifallah, S; Zmily, HD; Alqwasmi, AH; Zayed, H; Ghali, JK,期刊：Drugs of the Future, 页码：359-370 , 文章类型： Article，,卷期：2011年36-5] Hyponatremia is the most common electrolyte abnormality and has been associated with various morbidities, longer hospital stay and increased mortality. Until recently, options for treating hyponatremia were limited; howe... MDV-3100 Androgen Receptor Antagonist Prostate Cancer Therapy [作者：Gao, L; Alumkal, J,期刊：Drugs of the Future, 页码：371-376 , 文章类型： Article，,卷期：2011年36-5] Prostate cancer is the most common cancer in men in the U.S. and the second most lethal. Nearly all prostate cancer deaths occur due to castration-resistant prostate cancer (CRPC) that has progressed despite androgen dep... CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITORS AND THEIR ROLE IN CARDIOVASCULAR DISORDERS [作者：Kontush, A,期刊：Drugs of the Future, 页码：377-384 , 文章类型： Review，,卷期：2011年36-5] Low levels of high-density lipoprotein cholesterol (HDL-C) constitute a major independent cardiovascular risk factor. Novel strategies for raising HDL-C to address residual cardiovascular risk after statin treatment are ... COMBRETASTATIN DERIVATIVES IN CANCER: RECENT RESEARCH REVIEWED [作者：Pattillo, CB,期刊：Drugs of the Future, 页码：385-390 , 文章类型： Review，,卷期：2011年36-5] Combretastatin is a vascular disrupting agent that has been very effective in disrupting tumor blood flow, resulting in enhanced tumor killing. Combretastatin may have detrimental effects on normal tissue, so analogues w... HIF REGULATION IN TUMOR PROGRESSION AND ANGIOGENESIS AND POTENTIAL THERAPEUTIC AGENTS [作者：Podar, K,期刊：Drugs of the Future, 页码：391-402 , 文章类型： Review，,卷期：2011年36-5] The key transcription regulator hypoxia-inducible factor (HIF) is commonly overexpressed in a variety of human malignancies, including multiple myeloma. It regulates the transcription of a broad range of genes involved n... ERDHEIM-CHESTER DISEASE: NEW ADVANCES [作者：Haddley, K,期刊：Drugs of the Future, 页码：403-408 , 文章类型： Article，,卷期：2011年36-5] Erdheim-Chester disease (ECD) is a rare histiocytosis with a typical clinical phenotype of cortical sclerosis of long bones, detected using imaging techniques, and tissue infiltration by immune cells, detected by lesion ...