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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共17条记录   Regulation of developmental intercellular signalling by intracellular trafficking [作者：Shilo, BZ; Schejter, ED,期刊：EMBO journal, 页码：3516-3526 , 文章类型： Review，,卷期：2011年30-17] Universal trafficking components within the cell can be recruited to coordinate and regulate the developmental signalling cascades. We will present ways in which the intracellular trafficking machinery is used to affect ... Coupling viruses to dynein and kinesin-1 [作者：Dodding, MP; Way, M,期刊：EMBO journal, 页码：3527-3539 , 文章类型： Review，,卷期：2011年30-17] It is now clear that transport on microtubules by dynein and kinesin family motors has an important if not critical role in the replication and spread of many different viruses. Understanding how viruses hijack dynein an... Mechanisms of dendritic mRNA transport and its role in synaptic tagging [作者：Doyle, M; Kiebler, MA,期刊：EMBO journal, 页码：3540-3552 , 文章类型： Review，,卷期：2011年30-17] The localization of RNAs critically contributes to many important cellular processes in an organism, such as the establishment of polarity, asymmetric division and migration during development. Moreover, in the central n... Intercellular and systemic movement of RNA silencing signals [作者：Melnyk, CW; Molnar, A; Baulcombe, DC,期刊：EMBO journal, 页码：3553-3563 , 文章类型： Review，,卷期：2011年30-17] In most eukaryotes, double-stranded RNA is processed into small RNAs that are potent regulators of gene expression. This gene silencing process is known as RNA silencing or RNA interference (RNAi) and, in plants and nema... The road not taken: new destinations for yeast mRNAs on the move [作者：Yoo, S; Twiss, JL,期刊：EMBO journal, 页码：3564-3566 , 文章类型： Editorial Material，,卷期：2011年30-17] Highly specific and precise mechanisms have evolved for transport of mRNAs to subcellular regions in polarized eukaryotic cells. RNA localization is largely thought to be driven by RNA structures that are recognized by R... The five 'W's of transport [作者：Arnold, I; Brown, K,期刊：EMBO journal, 页码：3455-3456 , 文章类型： Editorial Material，,卷期：2011年30-17] Ran-dependent nuclear export mediators: a structural perspective [作者：Guttler, T; Gorlich, D,期刊：EMBO journal, 页码：3457-3474 , 文章类型： Review，,卷期：2011年30-17] Nuclear export is an essential eukaryotic activity. It proceeds through nuclear pore complexes (NPCs) and is mediated by soluble receptors that shuttle between nucleus and cytoplasm. RanGTPase-dependent export mediators ... Protein export at the ER: loading big collagens into COPII carriers [作者：Malhotra, V; Erlmann, P,期刊：EMBO journal, 页码：3475-3480 , 文章类型： Review，,卷期：2011年30-17] COPII vesicles mediate the export of secretory cargo from endoplasmic reticulum (ER) exit sites. However, of 60-90 nm diameter COPII vesicles are too small to accommodate secreted molecules such as the collagens. The ER ... Endosome maturation [作者：Huotari, J; Helenius, A,期刊：EMBO journal, 页码：3481-3500 , 文章类型： Review，,卷期：2011年30-17] Being deeply connected to signalling, cell dynamics, growth, regulation, and defence, endocytic processes are linked to almost all aspects of cell life and disease. In this review, we focus on endosomes in the classical ... Let's go bananas: revisiting the endocytic BAR code [作者：Qualmann, B; Koch, D; Kessels, MM,期刊：EMBO journal, 页码：3501-3515 , 文章类型： Review，,卷期：2011年30-17] Against the odds of membrane resistance, members of the BIN/Amphiphysin/Rvs (BAR) domain superfamily shape membranes and their activity is indispensable for a plethora of life functions. While crystal structures of diffe... Cotranslational transport of ABP140 mRNA to the distal pole of S. cerevisiae [作者：Kilchert, C; Spang, A,期刊：EMBO journal, 页码：3567-3580 , 文章类型： Article，,卷期：2011年30-17] In budding yeast, several mRNAs are selectively transported into the daughter cell in an actin-dependent manner by a specialized myosin system, the SHE machinery. With ABP140 mRNA, we now describe the first mRNA that is ... VCIP135 deubiquitinase and its binding protein, WAC, in p97ATPase-mediated membrane fusion [作者：Totsukawa, G; Kaneko, Y; Uchiyama, K; Toh, H; Tamura, K; Kondo, H,期刊：EMBO journal, 页码：3581-3593 , 文章类型： Article，,卷期：2011年30-17] Two distinct p97 membrane fusion pathways are required for Golgi biogenesis: the p97/p47 and p97/p37 pathways. VCIP135 is necessary for both pathways, while its deubiquitinating activity is required only for the p97/p47 ... Multiple modalities converge on a common gate to control K-2P channel function [作者：Bagriantsev, SN; Peyronnet, R; Clark, KA; Honore, E; Minor, DL,期刊：EMBO journal, 页码：3594-3606 , 文章类型： Article，,卷期：2011年30-17] Members of the K-2P potassium channel family regulate neuronal excitability and are implicated in pain, anaesthetic responses, thermosensation, neuroprotection, and mood. Unlike other potassium channels, K(2P)s are gated... The pore structure and gating mechanism of K2P channels [作者：Piechotta, PL; Rapedius, M; Stansfeld, PJ; Bollepalli, MK; Erhlich, G; Andres-Enguix, I; Fritzenschaft, H; Decher, N; Sansom, MSP; Tucker, SJ; Baukrowitz, T,期刊：EMBO journal, 页码：3607-3619 , 文章类型： Article，,卷期：2011年30-17] Two-pore domain (K2P) potassium channels are important regulators of cellular electrical excitability. However, the structure of these channels and their gating mechanism, in particular the role of the bundle-crossing ga... The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85 [作者：Oellerich, T; Bremes, V; Neumann, K; Bohnenberger, H; Dittmann, K; Hsiao, HH; Engelke, M; Schnyder, T; Batista, FD; Urlaub, H; Wienands, J,期刊：EMBO journal, 页码：3620-3634 , 文章类型： Article，,卷期：2011年30-17] Spleen tyrosine kinase Syk and its substrate SLP65 (also called BLNK) are proximal signal transducer elements of the B-cell antigen receptor (BCR). Yet, our understanding of signal initiation and processing is limited ow... Jarid2 regulates mouse epidermal stem cell activation and differentiation [作者：Mejetta, S; Morey, L; Pascual, G; Kuebler, B; Mysliwiec, MR; Lee, Y; Shiekhattar, R; Di Croce, L; Benitah, SA,期刊：EMBO journal, 页码：3635-3646 , 文章类型： Article，,卷期：2011年30-17] Jarid2 is required for the genomic recruitment of the polycomb repressive complex-2 (PRC2) in embryonic stem cells. However, its specific role during late development and adult tissues remains largely uncharacterized. He...