个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共18条记录   Use of molecular-dynamics simulation for optimizing protein stability: Consensus-designed ankyrin repeat proteins [作者：Winger, M; van Gunsteren, WF,期刊：Helvetica Chimica Acta, 页码：1605-1613 , 文章类型： Article，,卷期：2008年91-9] In earlier work, two highly homologous (87% sequence identity) ankyrin repeat (AR) proteins, E3_5 and E3_19, were studied using molecular-dynamics (MD) simulation. Their stabilities were compared, and it was found that t... gamma-cyclodextrin as inhibitor of the precipitation reaction between berberine and glycyrrhizin in decoctions of natural medicines: Interaction studies of cyclodextrins with glycyrrhizin and glycyrrhetic acid by H-1-NMR spectroscopy and molecular-dynamics calculation [作者：Kamigauchi, M; Kawanishi, K; Sugiura, M; Ohishi, H; Ishida, T,期刊：Helvetica Chimica Acta, 页码：1614-1624 , 文章类型： Article，,卷期：2008年91-9] To prevent the precipitation reaction between glycyrrhizin (1) and berberine (3) in the decoctions of Glycyrrhiza/Coptis rhizome or Glyqyrrhiza/Phellodendron bark, the presence of cyclodextrin (CD) in the mixture was pro... A simple multistep conversion of 1,2-dihydro-1,1-dimethoxynaphthalen-2-ones to (3,4-dihydro-3,4-dioxonaphthalen-2-yl)acetates [作者：Schmidt, K; Margaretha, P,期刊：Helvetica Chimica Acta, 页码：1625-1629 , 文章类型： Article，,卷期：2008年91-9] On irradiation (lambda = 350 nm) in the presence of 1,1-dimethoxyethene, naphthalene-1,2-dionemonoacetals 1 regioselectively afford 1,1,4,4-tetramethoxycyclobuta[a]naplithalen-3-ones 3. Sequential deprotection of these b... Triterpene saponins from the leaves of Ilex pernyi [作者：Xie, GB; Zheng, J; Tu, PF; Liu, GQ,期刊：Helvetica Chimica Acta, 页码：1630-1639 , 文章类型： Article，,卷期：2008年91-9] Eight new triterpene saponins, ilexpernosides C-J (1-8, resp.), and eight known triterpene saponins were isolated from the 70% EtOH extract of the leaves of Ilex pernyi. The structures of the new compounds were elucidate... Additional minor phytoecdysteroids of Serratula wolffii [作者：Simon, A; Liktor-Busa, E; Toth, G; Kele, Z; Groska, J; Bathori, M,期刊：Helvetica Chimica Acta, 页码：1640-1645 , 文章类型： Article，,卷期：2008年91-9] Three new and one known ecdysteroids were identified in the MeOH extract of the roots of Serratula wolffii. The new compounds isolated were (11 alpha)-11-hydroxyshidasterone (1), (2 beta,3 alpha,5 beta,14 beta,22R)-2,3,2... Studies on the chemistry of tetraamminezine(II) dipermanganate ([Zn(NH3)(4)](MnO4)(2)): Low-temperature synthesis of the manganese zinc oxide (ZnMn2O4) catalyst precursor [作者：Sajo, IE; Kotai, L; Keresztury, G; Gacs, I; Pokol, G; Kristof, J; Soptrayanov, B; Petrusevski, VM; Timpu, D; Sharma, PK,期刊：Helvetica Chimica Acta, 页码：1646-1658 , 文章类型： Article，,卷期：2008年91-9] Tetraamminezinc(II) dipermanganate ([Zn(NH3)(4)](MnO4)(2): 1) was prepared, and its structure was elucidated with XRD-Rictveld-refinement and vibrational-spectroscopy methods. Compound 1 has a cubic lattice consisting of... A novel meroterpene from Eurycorymbus cavaleriei [作者：Cheng, L; Song, ZH; Zhang, P; Zhang, M; Qu, HB; Ma, ZJ,期刊：Helvetica Chimica Acta, 页码：1659-1661 , 文章类型： Article，,卷期：2008年91-9] A novel symmetric dimeric compound, cavalerol (1), was isolated from the 95% EtOH extract of the twigs of Eurycorynibus cavaleriei. Compound 1 contains an unprecedented dimeric skeleton with two identical chiral meroterp... Synthesis and structures of two isomeric 4-diazo-2,3,4,5-tetrahydrofuran-3-ones [作者：Malashikhin, SA; Linden, A; Heimgartner, H; Rodina, LL; Nikolaev, VA,期刊：Helvetica Chimica Acta, 页码：1662-1669 , 文章类型： Article，,卷期：2008年91-9] The two regioisomeric 4-diazo-2,3,4,5-tetraliydrofuran-3-ones 6 and 7 were prepared via the common intermediate 2,3,4,5-tetrahydro-2,2-dimethyl-5,5-dipheiiylfuran-3-one (8). Diazo transfer with 2,4,6-triisopropylbenzenes... Layered-double-hydroxide-supported rhodium(0): An efficient and reusable catalyst for the Heck-type coupling of alkenes and arylboronic acids [作者：Roy, S; Roy, M; Trivedi, R,期刊：Helvetica Chimica Acta, 页码：1670-1674 , 文章类型： Article，,卷期：2008年91-9] Layered-double-hydroxide-supported nanorhodium catalyst (LDH-Rh(0)) was employed in the Heck-type coupling of alkenes 1 with arylboronic acids 2 to afford the corresponding substituted alkenes 3 in good to high yields (T... Oligonucleotide analogues with integrated bases and backbone - Part 18. Synthesis and association of thiomethylene-linked UU and AA dimers [作者：Ritter, A; Bernet, B; Vasella, A,期刊：Helvetica Chimica Acta, 页码：1675-1694 , 文章类型： Article，,卷期：2008年91-9] The thioinethylene-linked U*[s]U-(*) dimers 9-14 were synthesized by substitution of the 6[(mesyloxy)methyl]uridine 6 by the thiolate derived from the uridine-5'-thioacetates 7 and 8 followed by O-deprotection. Similarly... Chemical constituents from the bark of Garcinia xanthochymus and their 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activities [作者：Zhong, FF; Chen, Y; Yang, GZ,期刊：Helvetica Chimica Acta, 页码：1695-1703 , 文章类型： Article，,卷期：2008年91-9] A new bis-xanthone (xanthone = 9H-xantlien-9-one), named bigarcinenone A (1) which is the first example of a bis-xanthone with the xanthone-xanthone linkage between an aromatic C-atom and a C-5 side chain from a guttifer... Three escin-like triterpene saponins: Assamicins VI, VII, and VIII from the seeds of Aesculus assamica GRIFF [作者：Liu, HW; Wang, MY; Song, XY; Xia, Y; Zhao, YS; Song, XH; Jiang, MM; Zhang, X; Gao, H; Wang, NL; Yao, XS,期刊：Helvetica Chimica Acta, 页码：1704-1711 , 文章类型： Article，,卷期：2008年91-9] Three new escin-like triterpene saponins, assamicins VI (1), VII (2), and VIII (3), were isolated from the seeds of A. assamica, together with a known saponin, isoescin Ib (4). Their structures were established as 28-O-a... Two new eremophilane-type sesquiterpenoids from the rhizomes of Ligularia veitchiana (HEMSL.) GREENM [作者：Wang, CF; Zhao, Y; Liu, YZ; Zhang, ZZ,期刊：Helvetica Chimica Acta, 页码：1712-1716 , 文章类型： Article，,卷期：2008年91-9] Two new eremophilane-type sesquiterpenoids eremophil-6-en-11-ol (1) and (7 alpha,9 alpha,10 alpha)-9,10-epoxy-eremophilan-11-ol (2), together with a known eremophilane-type (6 alpha,8 alpha)-6,8-dihydroxyeremophil-7(11)-... A new triterpene and new sesquiterpenes from the roots of Ligularia sagitta [作者：Li, PL; Jia, ZJ,期刊：Helvetica Chimica Acta, 页码：1717-1727 , 文章类型： Article，,卷期：2008年91-9] One new triterpene and seven new eremophilane-type sesquiterpenes were isolated from the roots of Ligularia sagitta, among them la, an O-acetylated oleanane type triterpene, 2a and 3a, two 11-nor eremophilane-type sesqui... Triterpenoid ester saponins from Dipteronia dyeriana [作者：Guo, R; Luo, M; Long, CL; Li, ML; Ouyang, ZQ; Zhou, YP; Wang, YH; Li, XY; Shi, YN,期刊：Helvetica Chimica Acta, 页码：1728-1735 , 文章类型： Article，,卷期：2008年91-9] The phytochemical investigation of Dipteronia dyeriana (Aceraceae) resulted in the isolation and identification of five new triterpenoid ester saponins, dipterosides A-E (1-5). Their structures were elucidated by spectro... New open-chain and cyclic tetrapeptides, consisting of alpha-, beta(2)-, and beta(3)-amino-acid residues, as somatostatin mimics - A survey [作者：Seebach, D; Dubost, E; Mathad, RI; Jaun, B; Limbach, M; Loweneck, M; Flogel, O; Gardiner, J; Capone, S; Beck, AK; Widmer, H; Langenegger, D; Monna, D; Hoyer, D,期刊：Helvetica Chimica Acta, 页码：1736-1786 , 文章类型： Article，,卷期：2008年91-9] Cyclo-beta-tetrapeptides are known to adopt a conformation with an intramolecular transannular hydrogen bond in solution. Analysis of this structure reveals that incorporation of a beta(2)-amino-acid residue should lead ...