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[摘要]：A new bis-xanthone (xanthone = 9H-xantlien-9-one), named bigarcinenone A (1) which is the first example of a bis-xanthone with the xanthone-xanthone linkage between an aromatic C-atom and a C-5 side chain from a guttiferae plant, a new phloroglucinol (= benzene-1,3,5-triol) derivative, named garcinenone F (2), together with seven known xanthones were isolated from the bark of Garcinia xanthochymus. Their structures were elucidated by spectroscopic methods, especially 2D-NMR techniques. Bigarcinenone A (1) exhibited potent antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging test with a IC50 value of 9.2 mu m, compared to the positive control, the well-known antioxidant butylated hydroxytoluene (BHT) with a IC50 of 20 mu m (Table 3). |
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