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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共11条记录   Tunable, Post-translational Hydroxylation of Collagen Domains in Escherichia coli [作者：PINKAS DANIEL M; DING SHENG; RAINES RONALD T; BARRON ANNELISE E,期刊：ACS CHEMICAL BIOLOGY, 页码：320-324 , 文章类型： Article，,卷期：2011年6-4] Prolyl 4-hydroxylases are ascorbate-dependent oxygenases that play key roles in a variety of eukaryotic biological processes including oxygen sensing, siRNA regulation, and collagen folding. They perform their functions ... Monocyclic beta-Lactams Are Selective, Mechanism-Based Inhibitors of Rhomboid Intramembrane Proteases [作者：PIERRAT OLIVIER A; STRISOVSKY KVIDO; CHRISTOVA YONKA; LARGE JONATHAN; ANSELL KEITH; BOULOC NATHALIE; SMILJANIC ELA; FREEMAN MATTHEW,期刊：ACS CHEMICAL BIOLOGY, 页码：325-335 , 文章类型： Article，,卷期：2011年6-4] Rhomboids are relatively recently discovered intramembrane serine proteases that are conserved throughout evolution. They have a wide range of biological functions, and there is also much speculation about their potentia... Selection of Carbonic Anhydrase IX Inhibitors from One Million DNA-Encoded Compounds [作者：BULLER FABIAN; STEINER MARTINA; FREY KATHARINA; MIRCSOF DENNIS; SCHEUERMANN JOERG; KALISCH MARKUS; BUEHLMANN PETER; SUPURAN CLAUDIU T; NERI DARIO,期刊：ACS CHEMICAL BIOLOGY, 页码：336-344 , 文章类型： Article，,卷期：2011年6-4] DNA-encoded chemical libraries, i.e., collections of compounds individually coupled to distinctive DNA fragments serving as amplifiable identification barcodes, represent a new tool for the de novo discovery of small mol... Discovery of Cyclotides in the Fabaceae Plant Family Provides New Insights into the Cyclization, Evolution, and Distribution of Circular Proteins [作者：POTH AARON G; COLGRAVE MICHELLE L; PHILIP REYNOLD; KERENGA BOMAI; DALY NORELLE L; ANDERSON MARILYN A; CRAIK DAVID J,期刊：ACS CHEMICAL BIOLOGY, 页码：345-355 , 文章类型： Article，,卷期：2011年6-4] Cyclotides are plant proteins whose defining structural features are a head-to-tail cyclized backbone and three interlocking disulfide bonds, which in combination are known as a cyclic cystine knot. This unique structura... Mechanism of Vibrio cholerae Autoinducer-1 Biosynthesis [作者：WEI YUNZHOU; PEREZ LARK J; NG WAILEUNG; SEMMELHACK MARTIN F; BASSLER BONNIE L,期刊：ACS CHEMICAL BIOLOGY, 页码：356-365 , 文章类型： Article，,卷期：2011年6-4] Vibrio cholerae, the causative agent of the disease cholera, uses a cell to cell communication process called quorum sensing to control biofilm formation and virulence factor production. The major V. cholerae quorum-sens... Fluorescence and Atomic Force Microscopy Imaging of Wall Teichoic Acids in Lactobacillus plantarum [作者：ANDRE GUILLAUME; DEGHORAIN MARIE; BRON PETER A; VAN SWAM IRIS I; KLEEREBEZEM MICHIEL; HOLS PASCAL; DUFRENE YVES F,期刊：ACS CHEMICAL BIOLOGY, 页码：366-376 , 文章类型： Article，,卷期：2011年6-4] Although teichoic acids are major constituents of bacterial cell walls, little is known about the relationships between their spatial localization and their functional roles. Here, we used single-molecule atomic force mi... Dual Wavelength Photoactivation of cAMP- and cGMP-Dependent Protein Kinase Signaling Pathways [作者：PRIESTMAN MELANIE A; SUN LIANG; LAWRENCE DAVID S,期刊：ACS CHEMICAL BIOLOGY, 页码：377-384 , 文章类型： Article，,卷期：2011年6-4] The spatial and temporal organization of biological systems offers a level of complexity that is challenging to probe with conventional reagents. Photoactivatable (caged) compounds represent one strategy by which spatiot... The Nagoya Protocol and Natural Product-Based Research [作者：SOARES JITESH,期刊：ACS CHEMICAL BIOLOGY, 页码：289-289 , 文章类型： Editorial Material，,卷期：2011年6-4] Solubilization of a Membrane Protein by Combinatorial Supercharging [作者：HAJDUCZKI AGNES; MAJUMDAR SUDIPTA; FRICKE MARIE; BROWN ISOLA A M; WEISS GREGORY A,期刊：ACS CHEMICAL BIOLOGY, 页码：301-307 , 文章类型： Article，,卷期：2011年6-4] Hydrophobic and aggregation-prone, membrane proteins often prove too insoluble for conventional in vitro biochemical studies. To engineer soluble variants of human caveolin-1, a phage-displayed library of caveolin varian... Imaging LDL Receptor Oligonnerization during Endocytosis Using a Co-internalization Assay [作者：ZOU PENG; TING ALICE Y,期刊：ACS CHEMICAL BIOLOGY, 页码：308-313 , 文章类型： Article，,卷期：2011年6-4] Methods to Probe receptor oligomerization are useful to under. stand the molecular mechanisms of receptor signaling. Here we report a fluorescence imaging method to determine receptor oligomerization state in living cell... Small Molecule Inhibitors of Human DNA Polymerase lambda [作者：STRITTMATTER TOBIAS; BARETH BETTINA; IMMEL TIMO A; HUHN THOMAS; MAYER THOMAS U; MARX ANDREAS,期刊：ACS CHEMICAL BIOLOGY, 页码：314-319 , 文章类型： Article，,卷期：2011年6-4] To discover chemical probes to further understand the function of individual DNA polymerases,, we established a generally applicable high-throughput screening. By applying this technique we discovered three novel inhibit...