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One-Pot Three-Component Mild Synthesis of 2-Aryl-3-(9-alkylcarbazol-3-yl)thiazolidin-4-ones

  作者 LI ZHENG; ZHU ANGUO; YANG JINGYA  
  选自 期刊  Journal of Heterocyclic Chemistry;  卷期  2012年49-6;  页码  1458-1461  
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[摘要]A series of novel 2-aryl-3-(9-alkylcarbazol-3-yl)thiazolidin-4-ones were synthesized by one-pot three-component reactions of 3-amino-9-alkylcarbazoles, aromatic aldehydes, and 2-mercaptoacetic acid by using dicyclohexylcarbodiimide (DCC) as a cyclizing agent in dry diethyl ether at room temperature. This protocol has advantages of mild condition, short reaction time, high yield, and simple work-up procedure.

 
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