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Convenient One-Pot Two-Step Synthesis of 1,3-Thiazoles via Organocatalyzed Epoxidation of Nitroolefins

  作者 WEI SHENGWEI; WEISS KATHARINA M; TSOGOEVA SVETLANA B  
  选自 期刊  Synthesis;  卷期  2012年44-22;  页码  3441-3446  
  关联知识点  
 

[摘要]A convenient novel one-pot two-step strategy and its substrate scope for the synthesis of 1,3-thiazole heterocycles via organocatalytic epoxidation of nitroolefins with the TBHP/DBU system, and subsequent reaction of alpha-nitroepoxides with thioamides is reported.

 
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