Regioselective Syntheses of 2,7-(Het)Arylpyrido[ 2,3-d] pyrimidines by an Orthogonal Cross-Coupling Strategy

[摘要]：An efficient and easy access to 2,7-disubstituted pyrido[2,3-d] pyrimidine derivatives is reported. These derivatives were obtained using two orthogonal palladium-catalyzed cross-coupling reactions via successive C-7 chlorine and C-2 methylsulfur releases.

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