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Palladium-Catalyzed Intermolecular C3 Alkenylation of Indoles Using Oxygen as the Oxidant

  作者 CHEN WENLIANG; GAO YARU; MAO SHUAI; ZHANG YANLEI; WANG YUFEI; WANG YONGQIANG  
  选自 期刊  Organic Letters;  卷期  2012年14-23;  页码  5920-5923  
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[摘要]A general and efficient palladium-catalyzed intermolecular direct C3 alkenylation of indoles using oxygen as the oxidant has been developed. The reaction is of complete regio- and stereoselectivity. All products are E-isomers at the C3-position, and no Z-isomers or 2-substituted product can be detected.

 
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