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S(N)2 ' Reaction of Allylic Difluorides with Lithium Amides and Thiolates

  作者 BERGERON MAXIME; GUYADER DAVID; PAQUIN JEANFRANCOIS  
  选自 期刊  Organic Letters;  卷期  2012年14-23;  页码  5888-5891  
  关联知识点  
 

[摘要]The synthesis of monofluoroalkenes using an S(N)2' reaction of lithium amides derived from aromatic amines or lithium thiolates with 3,3-difluoropropenes is reported. This transformation features the use of fluoride as a leaving group.

 
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