Asymmetric Synthesis of the Fully Elaborated Pyrrolidinone Core of Oxazolomycin A

[摘要]：The asymmetric synthesis of the key pyrrolidinone core, including a highly elaborated exocyclic carbon chain, of the gamma-lactam beta-lactone antibiotic oxazolomycin A is described. Principal features include the Birch reduction of an aromatic pyrrole nucleus, a late stage RuO4 catalyzed pyrrolidine oxidation, and a highly diastereoselective organocerium addition to an aldehyde.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内