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Indium-Catalyzed Reductive Bromination of Carboxylic Acids Leading to Alkyl Bromides

  作者 MORIYA TOSHIMITSU; YONEDA SHINICHIRO; KAWANA KEITA; IKEDA REIKO; KONAKAHARA TAKEO; SAKAI NORIO  
  选自 期刊  Organic Letters;  卷期  2012年14-18;  页码  4842-4845  
  关联知识点  
 

[摘要]The combination of 1,1,3,3-tetramethyldisiloxane (TMDS) and trimethylbromosilane (Me3SiBr) with a catalytic amount of indium bromide (InBr3) undertook direct bromination of carboxylic acids, which produced the corresponding alkyl bromides in good to excellent yields. The reducing system was tolerant to several functional groups.

 
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