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pH responsive smart carrier of [60] fullerene with 6-amino-cyclodextrin inclusion complex for photodynamic therapy

  作者 NOBUSAWA KAZUYUKI; AKIYAMA MOTOFUSA; IKEDA ATSUSHI; NAITO MASANOBU  
  选自 期刊  Journal of Materials Chemistry;  卷期  2012年22-42;  页码  22610-22613  
  关联知识点  
 

[摘要]A new pH responsive smart carrier of C-60 was prepared with 6-amino-gamma-cyclodextrin (ACD) for photodynamic therapy. C-60 was rapidly released from its inclusion complex with ACD at pH 6.7, due to electrostatic repulsion between ammonium groups, followed by a rapid C-60 release at slightly acidic cancer cell surfaces.

 
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