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[摘要]：The primary objective was to determine the beneficial effects of oat beta-glucan (OG) and barley beta-glucan (BG) on gut health. A total of 200 male Sprague-Dawley rats were divided into 5 groups Of 40 rats each, control group (CON), low-dose OG-administered group (OGL), high-dose OG-administered group (OGH), low-dose BG-administered group (BGL), and high-dose BC-administered group (BGH). OGL and OGH were administered oat beta-glucan by intragastric gavage at a dose, of 0.35 g/kg of body Weight (BW) and 0.70 g/kg of BW. daily for 6 weeks, and BGL and BGH Were administered barley beta-glucan. The CON received normal saline. Intestinal-health-related indexes were analyzed at baseline, week 3, week 6, and week 7. Cereal beta-glucan significantly influenced the fecal water content, pH value, ammonia levels, beta-glucuronidase activity, azoreductase activity, and colonic short-chain fatty acid (SCFA) concentrations (p < 0.05). Moreover, the population of Lactobacillus and Bifidobacterium increased (p < 0.05), whereas the number of Enterobacteriaceae decreased (p < 0.05) in a dose-dependent manner during the period of cereal beta-glucan administration. These results suggested that cereal beta-glucan might exert favorable effects on improving intestinal functions and health but the gut-health-promoting effects of oat beta-glucan were better than those of barley beta-glucan. |
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