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A DNA based five-state switch with programmed reversibility

  作者 BURNS JONATHAN R; PREUS SOREN; SINGLETON DANIEL G; STULZ EUGEN  
  选自 期刊  Chemical Communications;  卷期  2012年48-90;  页码  11088-11090  
  关联知识点  
 

[摘要]A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin-porphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code.

 
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