Facile Synthesis of a Library of Lyme Disease Glycolipid Antigens

[摘要]：A library of one of the two Lyme disease antigens, BbGL1, has been synthesized in four steps from D-galactose using BF3-promoted glycosylation of the peracetate to introduce the cholesteryl beta-glycoside and TBTU-promoted esterification to add a range of fatty acids regioselectively at O-6 of D-galactose in good yield.

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