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[摘要]：The synthesis of some 3-(4-aryl-benzofuro[3,2-b]pyridin-2-yl)coumarins 3ar has been carried out by the reaction of 3-coumarinoyl methyl pyridinium salts 1ac with 2-arylidene aurones 2af in the presence of ammonium acetate and acetic acid under Krohnke's reaction conditions. All the synthesized compounds were characterized by analytical and spectral data. They have been screened for their antibacterial activity against Escherichia coli (ATCC 25922) as Gram-negative bacteria, Bacillus subtillis (ATCC 1633) as Gram-positive bacteria and antifungal activity against Aspergillus niger (ATCC 9029). |
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