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Synthesis of 1,3-Disubstituted Azetidines via a Tandem Ring-Opening Ring-Closing Procedure

  作者 MARCHCORTIJOS ANDREA; SNAPE TIMOTHY J; TURNER NICHOLAS J  
  选自 期刊  SYNLETT;  卷期  2012年-10;  页码  1511-1515  
  关联知识点  
 

[摘要]The synthesis of N-substituted symmetrical azetidines has been achieved in high yields via the reaction of primary amines undergoing an epoxide ring-opening reaction followed by an in situ ring-closing step.

 
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